Evidence map›Paper›PMID 39393800›Full record

ReviewSeminars in neurology2024

The Relationship between Delirium and Dementia.

Mfon E Umoh, Dennis Fitzgerald, Sarinnapha M Vasunilashorn, Esther S Oh, Tamara G Fong

Abstract readReview
In one paragraph

Review in Seminars in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mfon E UmohDivision of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Dennis FitzgeraldDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Sarinnapha M VasunilashornDivision of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Esther S OhDivision of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland.
Tamara G FongDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Utilizing Technology and AI Approaches to Facilitate Independence andResilience in Older AdultsP30AG073104 · NIA · JOHNS HOPKINS UNIVERSITY · PI Alexis Battle · 2021 to 2026
$31.2M
Addressing Hearing Loss as a Common Unmet Contributor to Neuropsychiatric SymptomsR01AG076525 · NIA · JOHNS HOPKINS UNIVERSITY · PI CARRIE L NIEMAN, Esther Seunghee Oh · 2022 to 2026
$3.9M
Health Services and Outcomes Research for Aging PopulationsT32AG066576 · NIA · JOHNS HOPKINS UNIVERSITY · PI CYNTHIA Melinda BOYD, Jennifer L. Wolff · 2020 to 2026
$3.8M
Brain Vulnerability in Delirium and Alzheimer’s Disease and Related Dementias: Intersection of Polygenic Risk and InflammationR01AG079864 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SARINNAPHA VASUNILASHORN · 2023 to 2026
$3.3M
Novel Blood Biomarker of Alzheimer's disease Using Oral Glucose ToleranceR01AG057725 · NIA · JOHNS HOPKINS UNIVERSITY · PI OH, ESTHER SEUNGHEE · 2017 to 2021
$2.4M
Does vestibular loss predict falls in patients with Alzheimer's Disease?R01AG057667 · NIA · JOHNS HOPKINS UNIVERSITY · PI OH, ESTHER SEUNGHEE · 2018 to 2022
$1.8M
Shared Pathophysiology of Postoperative Delirium and Alzheimer’s Disease and Related DementiasK01AG057836 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI VASUNILASHORN, SARINNAPHA · 2018 to 2022
$565k
NIA NIH HHS K01 AG057836NIA NIH HHS P30 AG021334NIA NIH HHS P30 AG073104NIA NIH HHS R01 AG057667NIA NIH HHS R01 AG057725NIA NIH HHS R01 AG076525NIA NIH HHS R01 AG079864NIA NIH HHS T32 AG066576
6 · The paper itself

Abstract

Delirium and dementia are common causes of cognitive impairment in older adults. They are distinct but interrelated. Delirium, an acute confusional state, has been linked to the chronic and progressive loss of cognitive ability seen in dementia. Individuals with dementia are at higher risk for delirium, and delirium itself is a risk factor for incident dementia. Additionally, delirium in individuals with dementia can hasten underlying cognitive decline. In this review, we summarize recent literature linking these conditions, including epidemiological, clinicopathological, neuroimaging, biomarker, and experimental evidence supporting the intersection between these conditions. Strategies for evaluation and diagnosis that focus on distinguishing delirium from dementia in clinical settings and recommendations for delirium prevention interventions for patients with dementia are presented. We also discuss studies that provide evidence that delirium may be a modifiable risk factor for dementia and consider the impact of delirium prevention interventions on long-term outcomes.

Indexed as

DeliriumDementiaHumansRisk Factors

Identifiers

PMID39393800
PMCPMC12323708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.