Evidence map›Paper›PMID 39393204›Full record

ReviewTissue & cell2024

Decellularization of various tissues and organs through chemical methods.

Tayebeh Sadat Tabatabai, Majid Salehi, Leila Rezakhani, Zohreh Arabpour, Ali R Djalilian, Morteza Alizadeh

Abstract readReview
In one paragraph

Review in Tissue & cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tayebeh Sadat TabatabaiStudent Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Majid SalehiTissue Engineering and Stem Cells Research Center, Shahroud University of Medical Sciences, Shahroud, Iran; Department of Tissue Engineering, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Leila RezakhaniFertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran; Department of Tissue Engineering, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Zohreh ArabpourDepartment of Ophthalmology and Visual Sciences, University of Illinois, Chicago, IL 60612, USA.
Ali R DjalilianDepartment of Ophthalmology and Visual Sciences, University of Illinois, Chicago, IL 60612, USA.
Morteza AlizadehDepartment of Tissue Engineering and Biomaterials, School of Advanced Medical Sciences and Technologies, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: Mor1361@gmail.com.

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SHUKLA, DEEPAK · 1985 to 2025
$14.8M
Novel Therapies for Ocular Chemical InjuriesR01EY024349 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DJALILIAN, ALI R · 2015 to 2020
$2.1M
Cell-derived therapies for corneal nerve repair: Structural and functional mechanismsR01EY035681 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALI R DJALILIAN, Mark I Rosenblatt · 2024 to 2026
$2.1M
NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY024349NEI NIH HHS R01 EY035681
6 · The paper itself

Abstract

Due to the increase in demand for donor organs and tissues during the past 20 years, new approaches have been created. These methods include, for example, tissue engineering in vitro and the production of regenerative biomaterials for transplantation. Applying the natural extracellular matrix (ECM) as a bioactive biomaterial for clinical applications is a unique approach known as decellularization technology. Decellularization is the process of eliminating cells from an extracellular matrix while preserving its natural components including its structural and functional proteins and glycosaminoglycan. This can be achieved by physical, chemical, or biological processes. A naturally formed three-dimensional structure with a biocompatible and regenerative structure is the result of the decellularization process. Decreasing the biological factors and antigens at the transplant site reduces the risk of adverse effects including inflammatory responses and immunological rejection. Regenerative medicine and tissue engineering applications can benefit from the use of decellularization, a promising approach that provides a biomaterial that preserves its extracellular matrix.

Indexed as

Tissue EngineeringAnimalsBiocompatible MaterialsDecellularized Extracellular MatrixExtracellular MatrixGlycosaminoglycansHumansRegenerative MedicineTissue ScaffoldsBiocompatible MaterialsDecellularized Extracellular MatrixGlycosaminoglycansAcellularizationEnzymaticExtracellular matrixPhysicalTissue

Identifiers

PMID39393204
PMCPMC11993266

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.