Evidence map›Paper›PMID 39392912›Full record

ArticleAmerican journal of audiology2024

Evidence of Peripheral Vestibular Impairment Among Adults With Chronic Moderate-Severe Traumatic Brain Injury.

Jessica J Feller, Melissa C Duff, Sharice Clough, Gary P Jacobson, Richard A Roberts, Daniel J Romero

Abstract read
In one paragraph

Article in American journal of audiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica J FellerDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0001-5659-8337
Melissa C DuffDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0003-1759-3634
Sharice CloughDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.
Gary P JacobsonDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0003-2950-1071
Richard A RobertsDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.
Daniel J RomeroDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Relational Memory as a Model of Behavioral (Dys)Function in Adults with Traumatic Brain InjuryR01NS110661 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COHEN, NEAL J., DUFF, MELISSA C · 2020 to 2024
$3.2M
NCATS NIH HHS UL1 TR002243NINDS NIH HHS R01 NS110661
6 · The paper itself

Abstract

purposeTraumatic brain injury (TBI) is a leading cause of death and disability among adults in the United States. There is evidence to suggest the peripheral vestibular system is vulnerable to damage in individuals with TBI. However, there are limited prospective studies that describe the type and frequency of vestibular impairment in individuals with chronic moderate-severe TBI (> 6 months postinjury).

methodCervical and ocular vestibular evoked myogenic potentials (VEMPs) and video head impulse test (vHIT) were used to assess the function of otolith organ and horizontal semicircular canal (hSCC) pathways in adults with chronic moderate-severe TBI and in noninjured comparison (NC) participants. Self-report questionnaires were administered to participants with TBI to determine prevalence of vestibular symptoms and quality of life associated with those symptoms.

resultsChronic moderate-severe TBI was associated with a greater degree of impairment in otolith organ, rather than hSCC, pathways. About 63% of participants with TBI had abnormal VEMP responses, compared to only ~10% with abnormal vHIT responses. The NC group had significantly less abnormal VEMP responses (~7%), while none of the NC participants had abnormal vHIT responses. As many as 80% of participants with TBI reported vestibular symptoms, and up to 36% reported that these symptoms negatively affected their quality of life.

conclusionsAdults with TBI reported vestibular symptoms and decreased quality of life related to those symptoms and had objective evidence of peripheral vestibular impairment. Vestibular testing for adults with chronic TBI who report persistent dizziness and imbalance may serve as a guide for treatment and rehabilitation in these individuals.

Indexed as

Brain Injuries, TraumaticVestibular DiseasesVestibular Evoked Myogenic PotentialsAdultAgedChronic DiseaseFemaleHead Impulse TestHumansMaleMiddle AgedOtolithic MembraneProspective StudiesQuality of LifeSemicircular CanalsVestibular Function Tests

Identifiers

PMID39392912
PMCPMC11622786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.