Evidence map›Paper›PMID 39392506›Full record

ReviewAnalytical and bioanalytical chemistry2025

Eco-friendly solvents in liquid-liquid microextraction techniques for biological and environmental analysis: a critical review.

Aldana A Lemos, Agostina L Chapana, Cecilia E Lujan, María B Botella, María N Oviedo, Rodolfo G Wuilloud

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aldana A LemosLaboratorio de Química Analítica Para Investigación y Desarrollo (QUIANID), Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Instituto Interdisciplinario de Ciencias Básicas (ICB), CONICET UNCUYO, Padre J. Contreras 1300, (5500), Mendoza, Argentina.
Agostina L ChapanaLaboratorio de Química Analítica Para Investigación y Desarrollo (QUIANID), Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Instituto Interdisciplinario de Ciencias Básicas (ICB), CONICET UNCUYO, Padre J. Contreras 1300, (5500), Mendoza, Argentina.
Cecilia E LujanLaboratorio de Química Analítica Para Investigación y Desarrollo (QUIANID), Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Instituto Interdisciplinario de Ciencias Básicas (ICB), CONICET UNCUYO, Padre J. Contreras 1300, (5500), Mendoza, Argentina.
María B BotellaLaboratorio de Química Analítica Para Investigación y Desarrollo (QUIANID), Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Instituto Interdisciplinario de Ciencias Básicas (ICB), CONICET UNCUYO, Padre J. Contreras 1300, (5500), Mendoza, Argentina.
María N OviedoLaboratorio de Química Analítica Para Investigación y Desarrollo (QUIANID), Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Instituto Interdisciplinario de Ciencias Básicas (ICB), CONICET UNCUYO, Padre J. Contreras 1300, (5500), Mendoza, Argentina.
Rodolfo G WuilloudLaboratorio de Química Analítica Para Investigación y Desarrollo (QUIANID), Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Instituto Interdisciplinario de Ciencias Básicas (ICB), CONICET UNCUYO, Padre J. Contreras 1300, (5500), Mendoza, Argentina. rwuilloud@mendoza-conicet.gob.ar.

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas Proyecto de Unidad Ejecutora (PUE)Fondo para la Investigación Científica y Tecnológica PICT-2019-03859Secretaría de Investigación, Internacionales y Posgrado, Universidad Nacional de Cuyo Proyecto 06/M035-T1
6 · The paper itself

Abstract

In recent years, green solvents have emerged as promising alternatives in the field of analytical chemistry, replacing conventional organic solvents known for their toxicity, volatility, and flammability. The combination of these solvents with liquid-liquid microextraction techniques has facilitated the development of simpler, faster, more economical, and environment-friendly methodologies for the analysis of samples of varying complexity. This review discusses the fundamental physicochemical properties and advantages of using deep eutectic solvents, ionic liquids, switchable-hydrophilicity solvents, supramolecular solvents, and surfactants as extractants. Furthermore, analytical methods based on liquid-liquid microextraction techniques developed in the last 5 years for the determination of organic compounds and metals in biological and environmental samples are presented and discussed, highlighting their applications and benefits to improve analytical performance and sustainability.

Indexed as

Environmental MonitoringEnvironmental PollutantsGreen Chemistry TechnologyLiquid Phase MicroextractionOrganic ChemicalsSolventsAnimalsHumansIonic LiquidsEnvironmental PollutantsIonic LiquidsOrganic ChemicalsSolventsBiological sampleEnvironmental sampleGreen solventLiquid–liquid microextractionSample preparation

Identifiers

PMID39392506

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.