Evidence map›Paper›PMID 39392391›Full record

ArticleOncotarget2024

Initiation of tumor dormancy by the lymphovascular embolus.

Yin Ye, Justin Wang, Michael G Izban, Billy R Ballard, Sanford H Barsky

Abstract read
In one paragraph

Article in Oncotarget, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yin YeDepartment of Pathology, Anatomy and Cell Biology and the Clinical and Translational Research Center of Excellence, Meharry Medical College, Nashville, TN 37208, USA.
Justin WangDepartment of Graduate Medical Education, Scripps Mercy Hospital, San Diego, CA 92103, USA.
Michael G IzbanDepartment of Pathology, Anatomy and Cell Biology and the Clinical and Translational Research Center of Excellence, Meharry Medical College, Nashville, TN 37208, USA.
Billy R BallardDepartment of Pathology, Anatomy and Cell Biology and the Clinical and Translational Research Center of Excellence, Meharry Medical College, Nashville, TN 37208, USA.
Sanford H BarskyDepartment of Pathology, Anatomy and Cell Biology and the Clinical and Translational Research Center of Excellence, Meharry Medical College, Nashville, TN 37208, USA.

Funding

Translational Pathology CoreU54CA163069 · NCI · MEHARRY MEDICAL COLLEGE · PI BALLARD, BILLY RAY · 2011 to 2025
$18.8M
NCI NIH HHS U54 CA163069
6 · The paper itself

Abstract

Cancer dormancy followed by recurrence remains an enigma in cancer biology. Since both local and systemic recurrences are thought to emanate from dormant micrometastasis which take origin from lymphovascular tumor emboli we wondered whether the process of dormancy might initiate within lymphovascular emboli. This study combines experimental studies with a patient-derived xenograft (PDX) of inflammatory breast cancer (Mary-X) that spontaneously forms spheroids

Indexed as

Breast NeoplasmsAnimalsCadherinsCell Line, TumorCell ProliferationFemaleHumansLymphatic MetastasisLymphatic VesselsMiceNeoplasm Recurrence, LocalNeoplastic Cells, CirculatingSignal TransductionSpheroids, CellularTOR Serine-Threonine KinasesCadherinsMTOR protein, humanTOR Serine-Threonine KinasesdormancyE-cadherin proteolysislymphovascular embolusmTOR

Identifiers

PMID39392391
PMCPMC11468568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.