Evidence map›Paper›PMID 39391972›Full record

ArticleJournal of paediatrics and child health2024

Evaluation of paediatric herpes zoster cases: Comparison of herpes zoster attacks in children with and without underlying conditions.

Aysel Gadimova, Gül Arga, Esra Çakmak Taşkın, Hatice Kübra Konca, Halil Özdemir, Hasan Fatih Çakmaklı, Elif İnce, Talia İleri, Handan Dinçaslan, Nurdan Taçyıldız and 4 more

Abstract readComparative Study
In one paragraph

Article in Journal of paediatrics and child health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Aysel GadimovaDepartment of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Gül ArgaDivision of Pediatric Infectious Disease, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.ORCID 0000-0002-4846-5945
Esra Çakmak TaşkınDivision of Pediatric Infectious Disease, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Hatice Kübra KoncaDivision of Pediatric Infectious Disease, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Halil ÖzdemirDivision of Pediatric Infectious Disease, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Hasan Fatih ÇakmaklıDivision of Pediatric Hematology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Elif İnceDivision of Pediatric Hematology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Talia İleriDivision of Pediatric Hematology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Handan DinçaslanDivision of Pediatric Oncology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Nurdan TaçyıldızDivision of Pediatric Oncology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Emel ÜnalDivision of Pediatric Oncology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Mehmet ErtemDivision of Pediatric Hematology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Erdal İnceDivision of Pediatric Infectious Disease, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Ergin ÇiftçiDivision of Pediatric Infectious Disease, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimHerpes zoster is rarely seen in children, but is more common and more severe in those with underlying medical conditions. The purpose of this study was to comprehensively evaluate cases of herpes zoster in all paediatric patients and to detail the clinical course and complications of this disease in children with and without underlying health problems in terms of similarities and differences.

methodsThe course of paediatric patients diagnosed with herpes zoster in a tertiary university hospital over a 19-year period was evaluated from the time of diagnosis, divided into groups with and without underlying disease.

resultsIn our study, where we evaluated 150 herpes zoster attacks in 143 children, 79.3% of the patients (n = 119) had underlying diseases, while 20.7% (n = 31) were healthy children. The age at the time of primary varicella-zoster virus and herpes zoster was significantly younger in the group without an underlying disease compared to the group with an underlying disease. Pain was reported more in the healthy group, and the duration of symptoms was longer. Ophthalmic nerve involvement was significantly higher in the group without a known disease. Treatment was administered in 90% of all attacks. In the group with underlying diseases, the duration of intravenous treatment and hospital stay were significantly higher as expected.

conclusionsThis study shows that herpes zoster attacks in healthy children can also progress with severe symptoms and complications. Approaches to reduce the burden of herpes zoster should be adopted and developed for all paediatric patients.

Indexed as

Herpes ZosterAdolescentAntiviral AgentsChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesAntiviral Agentshealthy childrenherpes zosterunderlying disease

Identifiers

PMID39391972
PMCPMC11616246

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.