Evidence map›Paper›PMID 39391804›Full record

ArticleACG case reports journal2024

Impact of Using Self-Assembling Peptide (PuraStat) on Anastomotic Ulcers-A Multicenter Case Series.

Veeral M Oza, Nitish Mittal, Charles Winchester, Yousef Fazel, Amar Manvar, Adam Goodman, Mohit Girotra, Harshit S Khara, Shivangi Kothari, Truptesh H Kothari

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Veeral M OzaBon Secours Mercy Health, Gastroenterology and Liver Disease, Greenville, SC.
Nitish MittalDivision of Gastroenterology, Hepatology, and Nutrition, The University of Texas Health Sciences Center, Houston, TX.
Charles WinchesterBon Secours Mercy Health, Gastroenterology and Liver Disease, Greenville, SC.
Yousef FazelDivision of Gastroenterology, Hepatology, and Nutrition, New York University Langone Long Island, Long Island, NY.
Amar ManvarDivision of Gastroenterology, Hepatology, and Nutrition, New York University Langone Long Island, Long Island, NY.
Adam GoodmanDivision of Gastroenterology, Hepatology, and Nutrition, New York University Langone Long Island, Long Island, NY.
Mohit GirotraElson S. Floyd College of Medicine, Washington State University, Seattle, WA.
Harshit S KharaDivision of Gastroenterology, Hepatology, and Nutrition, Geisinger Medical Center, Danville, PA.
Shivangi KothariDivision of Gastroenterology, Hepatology, and Nutrition, University of Rochester Medical Center and Strong Memorial Hospital, Rochester, NY.
Truptesh H KothariDivision of Gastroenterology, Hepatology, and Nutrition, University of Rochester Medical Center and Strong Memorial Hospital, Rochester, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of anastomotic ulcers, also known as marginal ulcers, is challenging, especially when established techniques have failed. PuraStat is a biocompatible synthetic peptide gel that is indicated for hemostasis of bleeding in the gastrointestinal tract and vascular anastomoses. We aim to evaluate the feasibility of PuraStat in the setting of nonhealing anastomotic ulcers when used alongside standard therapies. This is a multicenter case series of adult patients who had PuraStat applied with a follow-up repeat endoscopy. Nine out of 10 patients showed clinical improvement. We concluded that PuraStat is an effective agent to aid in healing of anastomotic ulcer.

Indexed as

anastomotic ulcerendoscopygastrointestinal bleedingPuraStat

Identifiers

PMID39391804
PMCPMC11466124

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.