Evidence map›Paper›PMID 39391745›Full record

ArticleACS materials letters2024

Hydrogel System with Independent Tailoring of Mechanics, CT, and US Contrasts for Affordable Medical Phantoms.

Haoyi Qiu, Jakob Nazarenus, Bernhard Egeler, Tom Thode, Firdaws Osman, Daniar Osmonov, Jörg Bahr, Sören Kaps, Frank-Andre Siebert, Reinhard Koch and 3 more

Abstract read
In one paragraph

Article in ACS materials letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Haoyi QiuFunctional Nanomaterials, Department of Materials Science, Kiel University, 24143 Kiel, Germany.ORCID https://orcid.org/0000-0003-2379-3333
Jakob NazarenusMultimedia Information Processing, Institute for Computer Science, Kiel University, 24118 Kiel, Germany.
Bernhard EgelerDepartment of Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Tom ThodeFunctional Nanomaterials, Department of Materials Science, Kiel University, 24143 Kiel, Germany.
Firdaws OsmanFunctional Nanomaterials, Department of Materials Science, Kiel University, 24143 Kiel, Germany.
Daniar OsmonovDepartment of Urology, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.
Jörg BahrFunctional Nanomaterials, Department of Materials Science, Kiel University, 24143 Kiel, Germany.
Sören KapsFunctional Nanomaterials, Department of Materials Science, Kiel University, 24143 Kiel, Germany.
Frank-Andre SiebertDepartment of Radiation Oncology, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Reinhard KochMultimedia Information Processing, Institute for Computer Science, Kiel University, 24118 Kiel, Germany.
Ulf LützenDepartment of Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.
Rainer AdelungFunctional Nanomaterials, Department of Materials Science, Kiel University, 24143 Kiel, Germany.ORCID https://orcid.org/0000-0002-2617-678X
Leonard SiebertFunctional Nanomaterials, Department of Materials Science, Kiel University, 24143 Kiel, Germany.ORCID https://orcid.org/0000-0001-5316-7240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical phantoms mimic aspects of procedures like computed tomography (CT), ultrasound (US) imaging, and surgical practices. However, the materials for current commercial phantoms are expensive and the fabrication with these is complex and lacks versatility. Therefore, existing material solutions are not suitable for creating patient-specific phantoms. We present a novel and cost-effective material system (utilizing ubiquitous sodium alginate hydrogel and coconut fat) with independently and accurately tailorable CT, US, and mechanical properties. By varying the concentration of alginate, cross-linker, and coconut fat, the radiological parameters and the elastic modulus were adjusted independently in a wide range. The independence was demonstrated by creating phantoms with features hidden in US, while visible in CT imaging and vice versa. This system is particularly beneficial in resource-scarce areas since the materials are cheap (<$ 1 USD/kg) and easy to obtain, offering realistic and versatile phantoms to practice surgeries and ultimately enhance patient care.

Identifiers

PMID39391745
PMCPMC11463687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.