Evidence map›Paper›PMID 39391717›Full record

ArticleiScience2024

Integration of multi-omics data revealed the orphan CpG islands and enhancer-dominated

Jiawei Yao, Penglei Yao, Yang Li, Ke He, Xinqi Ma, Qingsong Yang, Junming Jia, Zeren Chen, Shan Yu, Shuqing Gu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jiawei YaoDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Penglei YaoDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Yang LiDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Ke HeDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Xinqi MaDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Qingsong YangDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Junming JiaDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Zeren ChenDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Shan YuDepartment of Pathology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Shuqing GuDepartment of Neurosurgery, The First Hospital of Qiqihar, Qiqihar 161005, China.
Kunliang ChenDepartment of Neurosurgery, People's Hospital of the Daxing'an Mountain Range, Daxing'an Mountain Range 165300, China.
Yan ZhaoDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Weihua LiMedical Imaging Department, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen 518035, China.
Guangzhi WangDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Mian GuoDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complex transcriptional regulatory network leads to the poor prognosis of glioma. The role of orphan CpG islands (oCGIs) in the transcriptional regulatory network has been overlooked. We conducted a comprehensive exploration of the

Indexed as

BioinformaticsCancer systems biologyMedical informatics

Identifiers

PMID39391717
PMCPMC11465130

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.