Evidence map›Paper›PMID 39391697›Full record

ReviewFrontiers in pharmacology2024

Potential of traditional medicines in alleviating COVID-19 symptoms.

Moragot Chatatikun, Hiroko P Indo, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Yoshimasa Kitagawa, Hiroshi Ichikawa, Lunla Udomwech, Atthaphong Phongphithakchai, Orawan Sarakul and 7 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Moragot Chatatikun *School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.
Hiroko P Indo *Department of Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Motoki ImaiDepartment of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan.
Fumitaka KawakamiDepartment of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan.
Makoto KuboDepartment of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan.
Yoshimasa KitagawaOral Diagnosis and Medicine, Division of Oral Pathobiological Science, Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan.
Hiroshi IchikawaGraduate School of Life and Medical Sciences, Doshisha University, Kyoto, Japan.
Lunla UdomwechSchool of Medicine, Walailak University, Nakhon Si Thammarat, Thailand.
Atthaphong PhongphithakchaiDivision of Nephrology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Orawan SarakulSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.
Suriyan SukatiSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.
Voravuth SomsakSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.
Takafumi IchikawaDepartment of Regulation Biochemistry, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan.
Wiyada Kwanhian KlangbudMedical Technology Program, Faculty of Science, Nakhon Phanom University, Nakhon Phanom, Thailand.
Veeranoot NissapatornSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.
Jitbanjong TangpongSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.
Hideyuki J MajimaSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review discusses the prevention and treatment of coronavirus disease 2019 (COVID-19) caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Mutations in its spike glycoprotein have driven the emergence of variants with high transmissibility and immune escape capabilities. Some antiviral drugs are ineffective against the BA.2 subvariant at the authorized dose. Recently, 150 natural metabolites have been identified as potential candidates for development of new anti-COVID-19 drugs with higher efficacy and lower toxicity than those of existing therapeutic agents. Botanical drug-derived bioactive molecules have shown promise in dampening the COVID-19 cytokine storm and thus preventing pulmonary fibrosis, as they exert a strong binding affinity for viral proteins and inhibit their activity. The Health Ministry of Thailand has approved

Indexed as

botanical drugsCOVID-19immune evasionimmune reactionlong covidnatural metabolitesoxidative diseasetraditional medicine

Identifiers

PMID39391697
PMCPMC11464457

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.