ArticleGastroenterology report2024
Analysis of actionable gene fusions in a large cohort of Chinese patients with colorectal cancer.
Article in Gastroenterology report, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Impact of MMR status on preoperative CT-based lymph node overstaging in right-sided colon cancer: a retrospective analysis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- Identification and Characterization of a NovelInternational journal of molecular sciences · 2024Article
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Authors and funding
9 authors.
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Abstract
Background: The prevalence of gene fusion is extremely low in unselected patients with colorectal cancer (CRC). Published data on gene fusions are limited by relatively small sample sizes, with a primary focus on Western populations. This study aimed to analyse actionable gene fusions in a large consecutive Chinese CRC population. Methods: This study included 5,534 consecutive CRC patients from the Genecast database. Genomic profiling was performed using a panel of 769 cancer-related genes. Data for 34 CRC patients with actionable gene fusions were also collected from cBioPortal and ChimerSeq. Results: Among 5,534 CRC patients, 54 (0.98%) had actionable gene fusions, with Conclusions: Approximately 1% of the unselected Chinese CRC population carries actionable gene fusions, mostly involving
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