Evidence map›Paper›PMID 39391531›Full record

ArticleEuropean heart journal. Imaging methods and practice2024

Reference values of strain-derived myocardial work indices in heart transplant patients.

G E Mandoli, F Landra, L Tanzi, L Martini, C Fusi, C Sciaccaluga, E E Diviggiano, M Barilli, M C Pastore, M Focardi and 4 more

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In one paragraph

Article in European heart journal. Imaging methods and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

G E MandoliDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.ORCID https://orcid.org/0000-0002-3184-3006
F LandraDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.ORCID https://orcid.org/0000-0002-2106-0884
L TanziDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.
L MartiniDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.
C FusiDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.
C SciaccalugaDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.
E E DiviggianoDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.
M BarilliDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.
M C PastoreDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.ORCID https://orcid.org/0000-0002-7223-141X
M FocardiDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.
S BernazzaliDepartment of Cardiac Surgery, University of Siena, Siena, Italy.
M MaccheriniDepartment of Cardiac Surgery, University of Siena, Siena, Italy.
M CameliDivision of Cardiology, Department of Medical Biotechnologies, University of Siena, Viale Bracci 1, Siena 53100, Italy.ORCID https://orcid.org/0000-0003-3872-8964
M Y HeneinInstitute of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Myocardial work (MW) is a relatively novel non-invasive echocardiographic method with increasing fields of application. Normal reference ranges of MW indices in patients who have undergone a heart transplant (HTx) have not been determined yet. The aim of this study was to obtain the reference ranges for 2D echocardiographic indices of MW for adult HTx patients and to compare them with the results of the European Association of Cardiovascular Imaging (EACVI) Normal Reference Ranges for Echocardiography (NORRE) study. Methods and results: All consecutive HTx patients admitted at our institution (University Hospital of Siena, Italy) between September 2019 and May 2022 who underwent endomyocardial biopsy (EMB) were considered. Patients with a history of rejection, a history of coronary artery vasculopathy, either acute cellular rejection or acute antibody-mediated rejection at EMB, and donor-specific antibodies were excluded. MW retrospectively performed for the included patients was retrieved, and the results were compared with those from the EACVI NORRE study. Out of 176 HTx patients who underwent EMB, 94 patients were excluded. The study population consisted of 82 HTx patients [68.3% male, median age 53 (46-62) years]. The median duration from HTx was 5 (2-22) months. The main MW indices such as global work efficiency (GWE, 84 ± 8%), global work index (GWI, 1447 ± 409 mmHg%), global constructive work (GCW, 2067 ± 423 mmHg%), and global wasted work [GWW, 310 (217-499) mmHg%] did not differ according to gender. Each of these indices significantly differed from those reported in the EACVI NORRE study ( Conclusion: This study provides reference ranges for MW indices in an adult HTx population free from transplant-related complications which proved to be different from those previously reported in healthy volunteers.

Indexed as

echocardiographyheart transplantmyocardial workreference valuesspeckle tracking strain

Identifiers

PMID39391531
PMCPMC11465170

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