ArticleCureus2024
A Personalized Anisotropic Margin for Cervical Cancer Radiation Therapy Under the Guidance of Daily Iterative Cone-Beam Computed Tomography (iCBCT).
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Online adaptive radiation therapy (ART) eliminates interfraction uncertainties by adaption before each treatment session. However, intrafraction motions still exist and could become more severe due to long treatment time. Large isotropic margins can ensure clinical target volume (CTV) coverage but at the cost of more organs at risk damage. In this study, we proposed a novel personalized anisotropic margin search algorithm for cervical cancer radiation therapy under the guidance of daily iterative cone-beam computed tomography (iCBCT) to find the optimal margin values for each patient, which achieves the smallest possible planning target volume (PTV) and maintains CTV coverage. Twenty-two online Ethos ART treatment sessions were included for analysis. Two iCBCT scans were taken in each session. The first one (iCBCT
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