Evidence map›Paper›PMID 39391414›Full record

ArticleCureus2024

Longitudinal Incidence of Kidney/Urinary Stones in Individuals With Severe Motor and Intellectual Disabilities.

Kazuhiko Hashimoto, Shimpei Baba, Noriko Sumitomo, Eri Takeshita, Yuko Shimizu-Motohashi, Takashi Saito, Eiji Nakagawa, Masayuki Sasaki, Hirofumi Komaki

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kazuhiko HashimotoDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Shimpei BabaDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Noriko SumitomoDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Eri TakeshitaDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Yuko Shimizu-MotohashiDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Takashi SaitoDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Eiji NakagawaDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Masayuki SasakiDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.
Hirofumi KomakiDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objective and rationaleTo investigate the longitudinal incidence of kidney/urinary stones in patients with severe motor and intellectual disabilities and explore health burden events in patients with stone formation.

methodsThis was a retrospective, observational study. We identified patients with severe motor and intellectual disabilities who had the following: 1) admission to our hospital wards for >10 years; 2) two or more assessments for stone formation by ultrasonography or computed tomography; and 3) absence of kidney/urinary stones in the first imaging study. The Kaplan-Meier method was used to analyze the cumulative incidence of kidney/urinary stones. Recurrent urinary tract infections, hydronephrosis, renal dysfunction, and death were identified as health burdens.

resultsAmong the 41 patients (19 men, 22 women; median age, 28 years; range, 8-50 years), stone formation was detected in 11 (27%) patients during the observation period. The cumulative incidence rate of stone formation was 9.8% (95% confidence interval, 3.8-23.9) and 18.7% (95% confidence interval, 9.2-35.7) at five and 10 years, respectively. Death was frequently observed in patients with stone formation; six (55%) of the 11 patients with stone formation died during the follow-up period; two (15%) died among the other 30 patients without stone formation. However, only one patient with stone formation died in a renal event; the causal relationship between the stone formation and the deaths was not clarified.

conclusionThe longitudinal incidence of kidney/urinary stones was higher in patients with severe motor and intellectual disabilities than in the general population. Considering the difficulty of patients with severe motor and intellectual disabilities in conveying their symptoms, regular assessment of the kidney using abdominal imaging may be recommended.

Indexed as

cumulative incidence ratehealth burdenkidney/urinary stonesprognosissevere motor and intellectual disabilities

Identifiers

PMID39391414
PMCPMC11465612

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