Evidence map›Paper›PMID 39391313›Full record

ReviewFrontiers in immunology2024

Cross-omics strategies and personalised options for lung cancer immunotherapy.

Yalan Yan, Siyi Shen, Jiamin Li, Lanqian Su, Binbin Wang, Jinghan Zhang, Jiaan Lu, Huiyan Luo, Ping Han, Ke Xu and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yalan Yan *School of Clinical Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Siyi Shen *School of Clinical Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Jiamin Li *School of Clinical Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Lanqian SuSchool of Clinical Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Binbin WangIntensive Care Unit, Xichong People's Hospital, Nanchong, China.
Jinghan ZhangDepartment of Anaesthesiology, Southwest Medical University, Luzhou, China.
Jiaan LuSchool of Clinical Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Huiyan LuoDepartment of Oncology, Chongqing General Hospital, Chongqing University, Chongqing, China.
Ping HanDepartment of Oncology, Chongqing General Hospital, Chongqing University, Chongqing, China.
Ke XuDepartment of Oncology, Chongqing General Hospital, Chongqing University, Chongqing, China.
Xiang ShenDepartment of Respiratory and Critical Care Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Shangke HuangDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is one of the most common malignant tumours worldwide and its high mortality rate makes it a leading cause of cancer-related deaths. To address this daunting challenge, we need a comprehensive understanding of the pathogenesis and progression of lung cancer in order to adopt more effective therapeutic strategies. In this regard, integrating multi-omics data of the lung provides a highly promising avenue. Multi-omics approaches such as genomics, transcriptomics, proteomics, and metabolomics have become key tools in the study of lung cancer. The application of these methods not only helps to resolve the immunotherapeutic mechanisms of lung cancer, but also provides a theoretical basis for the development of personalised treatment plans. By integrating multi-omics, we have gained a more comprehensive understanding of the process of lung cancer development and progression, and discovered potential immunotherapy targets. This review summarises the studies on multi-omics and immunology in lung cancer, and explores the application of these studies in early diagnosis, treatment selection and prognostic assessment of lung cancer, with the aim of providing more personalised and effective treatment options for lung cancer patients.

Indexed as

GenomicsImmunotherapyLung NeoplasmsPrecision MedicineProteomicsAnimalsBiomarkers, TumorHumansMetabolomicsBiomarkers, Tumorimmune checkpointsimmunotherapyindividualised therapylung cancermulti-omicsprecision medicine

Identifiers

PMID39391313
PMCPMC11465239

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.