Evidence map›Paper›PMID 39391048›Full record

ArticleNeurotrauma reports2024

Timing of Surgery and Preoperative Predictors of Surgical Site Infections for Patients with Depressed Skull Fractures in a Sub-Saharan Tertiary Hospital: A Prospective Cohort Study.

Hervé Monka Lekuya, Jelle Vandersteene, Larrey Kasereka Kamabu, Rose Nantambi, Ronald Mbiine, Anthony Kirabira, Fredrick Makumbi, Stephen Cose, David Patrick Kateete, Mark Kaddumukasa and 3 more

Abstract read
In one paragraph

Article in Neurotrauma reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hervé Monka LekuyaDepartment of Surgery/Neurosurgery, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID https://orcid.org/0000-0003-1913-4378
Jelle VandersteeneDepartment of Human Structure and Repair/Neurosurgery UZ Gent, Ghent University, Ghent, Belgium.
Larrey Kasereka KamabuDepartment of Surgery/Neurosurgery, College of Health Sciences, Makerere University, Kampala, Uganda.
Rose NantambiDepartment of Surgery/Neurosurgery, College of Health Sciences, Makerere University, Kampala, Uganda.
Ronald MbiineDepartment of Surgery/Neurosurgery, College of Health Sciences, Makerere University, Kampala, Uganda.
Anthony KirabiraSchool of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Fredrick MakumbiSchool of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Stephen CoseMedical Research Council/London School of Hygiene & Tropical Medicine, MRC Uganda, Entebbe ,Uganda.
David Patrick KateeteDepartment of Molecular Biology, College of Health Sciences, Makerere University, Kampala, Uganda.
Mark KaddumukasaDepartment of Internal Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Edward BaertDepartment of Human Structure and Repair/Neurosurgery UZ Gent, Ghent University, Ghent, Belgium.
Moses GalukandeDepartment of Surgery/Neurosurgery, College of Health Sciences, Makerere University, Kampala, Uganda.
Jean-Pierre Okito KalalaDepartment of Human Structure and Repair/Neurosurgery UZ Gent, Ghent University, Ghent, Belgium.

Funding

Research training and mentorship to strengthen brain health across the lifespan in Uganda.D43NS118560 · NINDS · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KADDUMUKASA, MARK, KATABIRA, ELLY T · 2020 to 2024
$1.1M
NINDS NIH HHS D43 NS118560
6 · The paper itself

Abstract

Surgical site infections (SSIs) remain a major cause of life-threatening morbidity following surgery for depressed skull fractures (DSFs) among patients with traumatic brain injury (TBI). The timing of the surgery for DSF has been questioned as a risk of SSI without a clear cutoff. We aimed to compare the risk of SSI within 3 months between surgery done before versus after 48 h of injury and with its preoperative predictors. We conducted a prospective cohort study at Mulago Hospital, Uganda. Patients with mild-to-moderate TBI with DSF were followed up perioperatively from the operating time up to 3 months. The outcome variables were the incidence risk of SSI, types of SSI, microbial culture patterns of wound isolates, and hospital length of stay. We enrolled 127 patients with DSF, median age = 24 (interquartile range [IQR] = 17-31 years), 88.2% (112/127) male, and assault victims = 53.5%. The frontal bone involved 59%, while 50.4% had a dural tear. The incidence of SSI was 18.9%, mainly superficial incisional infection; Gram-negative microorganisms were the most common isolates (64.7%). The group of surgical intervention >48 h had an increased incidence of SSI (57.3% vs. 42.7%,

Indexed as

depressed skull fracturespneumocraniumsurgical site infectionsurgical timing

Identifiers

PMID39391048
PMCPMC11462418

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.