Evidence map›Paper›PMID 39390258›Full record

ArticleEMBO reports2024

Structural insights into human zinc transporter ZnT1 mediated Zn

Yonghui Long, Zhini Zhu, Zixuan Zhou, Chuanhui Yang, Yulin Chao, Yuwei Wang, Qingtong Zhou, Ming-Wei Wang, Qianhui Qu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EMBO reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. ZIP-ZnT1 complexes mediate a local ZnCellular and molecular life sciences : CMLS · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yonghui Long *Shanghai Stomatological Hospital, School of Stomatology, Institutes of Biomedical Sciences, Fudan University, 200032, Shanghai, China.ORCID 0000-0001-6412-8415
Zhini Zhu *Shanghai Stomatological Hospital, School of Stomatology, Institutes of Biomedical Sciences, Fudan University, 200032, Shanghai, China.ORCID 0009-0001-8750-7300
Zixuan Zhou *Shanghai Stomatological Hospital, School of Stomatology, Institutes of Biomedical Sciences, Fudan University, 200032, Shanghai, China.
Chuanhui Yang *Shanghai Stomatological Hospital, School of Stomatology, Institutes of Biomedical Sciences, Fudan University, 200032, Shanghai, China.ORCID 0009-0002-4084-1966
Yulin Chao *Shanghai Stomatological Hospital, School of Stomatology, Institutes of Biomedical Sciences, Fudan University, 200032, Shanghai, China.
Yuwei WangShanghai Stomatological Hospital, School of Stomatology, Institutes of Biomedical Sciences, Fudan University, 200032, Shanghai, China.ORCID 0000-0002-3265-539X
Qingtong ZhouDepartment of Pharmacology, School of Basic Medical Sciences, Fudan University, 200032, Shanghai, China.
Ming-Wei WangResearch Center for Deepsea Bioresources, 572025, Sanya, Hainan, China.ORCID 0000-0001-6550-9017
Qianhui QuShanghai Stomatological Hospital, School of Stomatology, Institutes of Biomedical Sciences, Fudan University, 200032, Shanghai, China. qqh@fudan.edu.cn.ORCID 0000-0002-5753-2599

Funding

China Postdoctoral Science Foundation (China Postdoctoral Foundation Project) 2022M720805Ministry of Science and Technology of the People's Republic of China (MOST) 2023YFA0915000MOST | National Natural Science Foundation of China (NSFC) 32171194MOST | National Natural Science Foundation of China (NSFC) 32371256
6 · The paper itself

Abstract

Zinc transporter 1 (ZnT1), the principal carrier of cytosolic zinc to the extracellular milieu, is important for cellular zinc homeostasis and resistance to zinc toxicity. Despite recent advancements in the structural characterization of various zinc transporters, the mechanism by which ZnTs-mediated Zn

Indexed as

Cation Transport ProteinsCryoelectron MicroscopyMolecular Dynamics SimulationZincBinding SitesBiological TransportHumansHydrogen-Ion ConcentrationModels, MolecularProtein BindingProtein ConformationProtein DomainsProtein MultimerizationCation Transport ProteinsSLC30A1 protein, humanZincHZinc homeostasisH+/Zn2+ ExchangeZinc TransporterZnT1/SLC30A1ZnT3/SLC30A3

Identifiers

PMID39390258
PMCPMC11549101

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.