Evidence map›Paper›PMID 39389969›Full record

Trial reportNature communications2024

Xiuling Shen, Haoyi Zhou, Xin Zhou, Zongchao Liu, Xiangxi Meng, Linyu Zhang, Yufei Song, Rui Guo, Fei Wang, Kui Li and 4 more

Abstract readClinical Trial, Phase IClinical Trial, Phase II
In one paragraph

Trial report in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Whole-body CD8Nature communications · 2025
    Trial
  2. Review
  3. Improved early response assessment of chemoimmunotherapy efficacy byEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Imaging the hallmarks of cancer.Nature reviews. Cancer · 2026
    Review
  5. European journal of nuclear medicine and molecular imaging · 2026
    Article
  6. Review
  7. Immuno-positron emission tomography in cardiovascular disease: Advances, challenges, and opportunities.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2026
    Review
  8. Article
  9. Challenges in tracer development for tumor microenvironment (TME) imaging.European journal of nuclear medicine and molecular imaging · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Granzyme B PET/CT predicts chemo-immunotherapy outcomes in microsatellite stable gastric cancers.European journal of nuclear medicine and molecular imaging · 2026
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Imaging the fate of CAR-T cellsFrontiers in immunology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiuling Shen *Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China.
Haoyi Zhou *State Key Laboratory of Vascular Homeostasis and Remodeling, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China.
Xin ZhouKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China.
Zongchao LiuState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, 100142, Beijing, China.ORCID 0000-0002-2008-3793
Xiangxi MengKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China.ORCID 0000-0002-6590-011X
Linyu ZhangState Key Laboratory of Vascular Homeostasis and Remodeling, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China.
Yufei SongKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China.
Rui GuoKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China.
Fei WangKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China.
Kui LiState Key Laboratory of Vascular Homeostasis and Remodeling, Department of Radiation Medicine, School of Basic Medical Sciences, Peking University Health Science Center, 100191, Beijing, China.
Wenqing LiState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, 100142, Beijing, China.ORCID 0000-0002-8336-5552
Zhi YangKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China. pekyz@163.com.ORCID 0000-0003-2084-5193
Zhaofei LiuKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China. liuzf@bjmu.edu.cn.ORCID 0000-0001-8718-8154
Nan LiKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, 100142, Beijing, China. rainbow6283@sina.com.ORCID 0000-0001-8619-7550

Funding

Beijing Nova Program 20220484182National Natural Science Foundation of China (National Science Foundation of China) 81920108020 and 82325028Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) Z220011 and Z220014
6 · The paper itself

Abstract

To tackle the clinical challenge of noninvasively assessing immunotherapy efficacy in patients, here we used positron emission tomography (PET) with

Indexed as

GranzymesImmunotherapyLymphomaPositron-Emission TomographyAdultAgedCD8-Positive T-LymphocytesFemaleGallium RadioisotopesHumansImmune Checkpoint InhibitorsMaleMiddle AgedNeoplasmsProgression-Free SurvivalTissue DistributionGallium RadioisotopesGranzymesGZMB protein, humanImmune Checkpoint Inhibitors

Identifiers

PMID39389969
PMCPMC11467221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.