Evidence map›Paper›PMID 39389242›Full record

ArticleJournal of structural biology2024

Transcriptome profiling of DPP stimulated DPSCs identifies the role of autophagy in odontogenic differentiation.

Yinghua Chen, Cassandra Villani, Amudha Ganapathy, Anne George

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of structural biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yinghua ChenDepartment of Oral Biology, University of Illinois Chicago, Chicago, IL 60612, USA.
Cassandra VillaniDepartment of Oral Biology, University of Illinois Chicago, Chicago, IL 60612, USA.
Amudha GanapathyDepartment of Oral Biology, University of Illinois Chicago, Chicago, IL 60612, USA.
Anne GeorgeDepartment of Oral Biology, University of Illinois Chicago, Chicago, IL 60612, USA. Electronic address: anneg@uic.edu.

Funding

Role of DMP1 Mediated Paracrine Signaling in VasculogenesisR01DE031737 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Anne George · 2022 to 2026
$2.5M
The Role of DPP in Dental Pulp Stem Cells and its Potential in Tissue RegenerationR01DE028531 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GEORGE, ANNE · 2019 to 2023
$1.9M
NIDCR NIH HHS R01 DE028531NIDCR NIH HHS R01 DE031737
6 · The paper itself

Abstract

Dentin phosphophoryn (DPP), synthesized and processed predominantly by the odontoblasts, serves both a structural and signaling role in dentin. In the ECM, DPP functions as an avid calcium and collagen binding protein and it also plays a crucial role as a scaffold for cell attachment and survival. The signaling function of DPP was demonstrated when undifferentiated mesenchymal cells stimulated with DPP, mediated calcium signaling through release of intracellular Ca

Indexed as

AutophagyCell DifferentiationDental PulpExtracellular Matrix ProteinsGene Expression ProfilingOdontoblastsOdontogenesisPhosphoproteinsSialoglycoproteinsAutophagy-Related Protein 5Beclin-1Cells, CulturedDentin SialophosphoproteinHumansMicrotubule-Associated ProteinsStem CellsATG5 protein, humanAutophagy-Related Protein 5Beclin-1Dentin SialophosphoproteinExtracellular Matrix ProteinsMAP1LC3A protein, humanMicrotubule-Associated ProteinsPhosphoproteinsSialoglycoproteins

Identifiers

PMID39389242
PMCPMC12065480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.