Evidence map›Paper›PMID 39388726›Full record

ArticleJournal of radiation research2024

Internal radiation dose estimates in organs of Wistar rats exposed to sprayed neutron-activated 31SiO2 microparticles: first results of international multicenter study.

Valeriy Stepanenko, Hitoshi Sato, Andrey Kaprin, Nariaki Fujimoto, Almagul Kushugulova, Sergey Ivanov, Peter Shegay, Viktoria Bogacheva, Alexey Petukhov, Kassym Zhumadilov and 9 more

Abstract read
In one paragraph

Article in Journal of radiation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Valeriy StepanenkoA. Tsyb Medical Radiological Research Center, Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Koroleva St., Obninsk, Kaluga Region 249036, Russian Federation.
Hitoshi SatoIbaraki Prefectural University of Health Sciences, 4669-2 Ami, Ami-machi, Inashiki-gun, Ibaraki 300-0394, Japan.
Andrey KaprinNational Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4, Koroleva Str., Obninsk, Kaluga Region 249036, Russian Federation.
Nariaki FujimotoResearch Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
Almagul KushugulovaNazarbayev University, 53 Kabanbay Batyr Avenue, Astana City 010000, Republic of Kazakhstan.
Sergey IvanovA. Tsyb Medical Radiological Research Center, Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Koroleva St., Obninsk, Kaluga Region 249036, Russian Federation.
Peter ShegayNational Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4, Koroleva Str., Obninsk, Kaluga Region 249036, Russian Federation.
Viktoria BogachevaA. Tsyb Medical Radiological Research Center, Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Koroleva St., Obninsk, Kaluga Region 249036, Russian Federation.
Alexey PetukhovA. Tsyb Medical Radiological Research Center, Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation, 4 Koroleva St., Obninsk, Kaluga Region 249036, Russian Federation.
Kassym ZhumadilovInternational Department of Nuclear Physics, New Materials and Technology, L. N. Gumilyov Eurasian National University, 13 Munaitpasova St., Astana City 010008, Republic of Kazakhstan.
Evgenia OstroumovaEnvironment and Lifestyle Epidemiology Branch, International Agency for Research on Cancer/WHO, 25 Avenue Tony Garnier, Lyon 69366, France.
Hiroshi YasudaResearch Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
Noriyuki KawanoThe Center for Peace, Hiroshima University, Higashisenda-machi 1-1-89, Naka-ku, Hiroshima 730-0053, Japan.
Megu OhtakiThe Center for Peace, Hiroshima University, Higashisenda-machi 1-1-89, Naka-ku, Hiroshima 730-0053, Japan.
Satoru EndoGraduate School of Advanced Science and Engineering, Hiroshima University, 1-4-1, Kagamiyama, Higashi, Hiroshima 739-8527, Japan.
Aya SakaguchiInstitute of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan.
Laura ChulenbayevaNazarbayev University, 53 Kabanbay Batyr Avenue, Astana City 010000, Republic of Kazakhstan.
Nurislam MukhanbetzhanovNazarbayev University, 53 Kabanbay Batyr Avenue, Astana City 010000, Republic of Kazakhstan.
Masaharu HoshiThe Center for Peace, Hiroshima University, Higashisenda-machi 1-1-89, Naka-ku, Hiroshima 730-0053, Japan.

Funding

A. Tsyb Medical Radiological Research Center-Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian FederationEnvironmental Radioactivity Research Network Center F23-14Grant of Ministry of Science and Higher Education of the Republic of Kazakhstan AP19678341Japan Society for the Promotion of Science KAKENHI JP19KK0266L.N. Gumilyov Eurasian National UniversityMinistry of Science and Higher Education of the Republic of Kazakhstan AP23484543World Health Organization 001
6 · The paper itself

Abstract

Neutron-activated 31Si is an almost pure beta emitter and is one of the short-lived radionuclides, including beta-gamma emitter 56Mn, which were created in a form of residual radioactivity in the early period after the atomic bombing of Hiroshima and Nagasaki. The features of the biological effects of internal irradiation by these radionuclides are a subject of scientific discussions and research. The publication presents data on internal radiation doses in experimental Wistar rats that were exposed to sprayed neutron-activated microparticles of 31SiO2. Doses of internal radiation could be conditionally divided into three groups according to their values. It has been found that elevated values of internal radiation doses in rats' organs/tissues as a result of exposure to sprayed 31SiO2 microparticles with initial activity of 3.2 × 107 Bq varied from 10 to 120 mGy (eyes, lungs, skin, stomach, jejunum, large intestine). The moderate dose values were in the range from 1.9 to 3.7 mGy (trachea, esophagus, ileum). The smallest doses were received by the kidney, testis, blood, cerebellum, heart, liver, cerebrum, bladder, spleen and thymus (from 0.11 to 0.94 mGy). The obtained data are important for interpreting the results of ongoing and planned biological experiments with 31SiO2 microparticles-in comparison with the previously published data on features of biological effects caused by beta-gamma emitting 56MnO2 neutron-activated microparticles.

Indexed as

NeutronsRadiation DosageRats, WistarSilicon DioxideAnimalsDose-Response Relationship, RadiationMaleNeutron Activation AnalysisRatsSilicon Dioxide31SiO2atomic bombingdosimetryinternal irradiationneutron activationradioactive microparticlesWistar rats

Identifiers

PMID39388726
PMCPMC11630057

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.