Evidence map›Paper›PMID 39388028›Full record

ArticleMarine biotechnology (New York, N.Y.)2024

Chemical Survey and Antifungal Efficacy of Sargassum muticum's Alkaloids and Phenolic-Rich Fraction Against Airborne Toxigenic and Nosocomial Opportunistic Molds Isolates.

Houda Younssi Tarhzouti, Badr-Ddine El Mouns, Hayat Ben-Saghroune, Sara Haida, Selma Mabrouki, Fatima Lakhdar, Samira Etahiri

Abstract read
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In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Houda Younssi TarhzoutiLaboratory of Marine Biotechnology and Environment, Department of Biology, CNRST Labeled Research Unit, Faculty of Sciences, ChouaibDoukkali University, BP 20, 24000, El Jadida, Morocco. younssitarhzoutihouda@gmail.com.
Badr-Ddine El MounsLaboratory of Marine Biotechnology and Environment, Department of Biology, CNRST Labeled Research Unit, Faculty of Sciences, ChouaibDoukkali University, BP 20, 24000, El Jadida, Morocco.
Hayat Ben-SaghrouneHigher Institute of Nursing Professions and Health Techniques, Fez, Morocco.
Sara HaidaLaboratory of Advanced Materials and Process Engineering, Department of Chemistry, Faculty of Science, Ibn Tofail University, 133-14000, Kenitra, Morocco.
Selma MabroukiLaboratory of Marine Biotechnology and Environment, Department of Biology, CNRST Labeled Research Unit, Faculty of Sciences, ChouaibDoukkali University, BP 20, 24000, El Jadida, Morocco.
Fatima LakhdarLaboratory of Marine Biotechnology and Environment, Department of Biology, CNRST Labeled Research Unit, Faculty of Sciences, ChouaibDoukkali University, BP 20, 24000, El Jadida, Morocco.
Samira EtahiriLaboratory of Marine Biotechnology and Environment, Department of Biology, CNRST Labeled Research Unit, Faculty of Sciences, ChouaibDoukkali University, BP 20, 24000, El Jadida, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Atlantic coastline of El-Jadida, Morocco, is renowned for its plentiful algae, especially brown seaweed, which is rich in active compounds known for their antifungal properties. This valuable resource offers an exciting opportunity to tackle the numerous challenges posed by invasive fungal infections, allergies, mycotoxin-related food poisoning, and drug-resistant strains. Underscoring the urgent need to explore alternative, sustainable, and environmentally friendly antifungal agents derived from algae. This study aimed to evaluate the antifungal activity of total alkaloids and phenolic-rich fractions derived from seven species of Pheophyceae: Sargassum muticum, Sargassum vulgare, Bifurcaria bifurcata, Cystoseira tamariscifolia, Cystoseira humilis, Laminaria ochroleuca, and Fucus spiralis against four fungi: airborne toxigenic isolates of Aspergillus westerdijkiae and Chaetomium globosum as well as nosocomial opportunistic isolates of Aspergillus nidulans and Scopulariopsis brevicaulis. The study also aimed to identify the most effective alga and its specific active compounds through LC-MS and GC-MS analysis. The invasive Sargassum muticum was chosen as the most potent alga in inhibiting the growth of mycelium. For the first time, the alkaloids palmatine and jatrorrhizine, along with caulerpin, have been identified. The chloroform fraction revealed the prevalence of phenolic compounds including, phenolic acids, flavonoids, and phlorotannins. The lowest minimum inhibitory concentrations (MICs), with a maximum fungal load of 10

Indexed as

AlkaloidsAntifungal AgentsSargassumAir MicrobiologyAspergillusFungiMicrobial Sensitivity TestsMoroccoPhaeophyceaePhenolsAlkaloidsAntifungal AgentsPhenolsAlkaloidsAntifungal activityGC–MSHPLC–MSPhenolic-rich fractionSargassum muticum

Identifiers

PMID39388028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.