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ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2024

Transient vertical diplopia following ibuprofen intake: a case report.

Shalom Haggiag, Luca Prosperini, Federico Sadun, Alessandro Stasolla, Davide Lonati, Claudio Gasperini, Carla Tortorella

Abstract readCase Reports
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Shalom HaggiagDepartment of Neuroscience, Azienda Ospedaliera San Camilo Forlanini, Rome, Italy. neuroshalom@hotmail.com.ORCID http://orcid.org/0000-0002-5569-4121
Luca ProsperiniDepartment of Neuroscience, Azienda Ospedaliera San Camilo Forlanini, Rome, Italy.
Federico SadunNeuroOphthalmology Unit, Presidio Ospedaliero Oftalmico, Rome, Italy.
Alessandro StasollaNeuroradiology Unit, Azienda Ospedaliera San Camilo Forlanini, Rome, Italy.
Davide LonatiPavia Poison Centre, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Claudio GasperiniDepartment of Neuroscience, Azienda Ospedaliera San Camilo Forlanini, Rome, Italy.
Carla TortorellaDepartment of Neuroscience, Azienda Ospedaliera San Camilo Forlanini, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ibuprofen, a commonly used over-the-counter medication, is widely recognized for its effective pain relief properties but is also associated with various adverse effects, including rare ocular and neurological manifestations. We report a case of a 27-year-old male who experienced transient vertical diplopia following a standard ibuprofen dosage for back pain. Symptoms resolved promptly upon discontinuation of the drug, with normal findings on extensive clinical and laboratory evaluations. The clinical presentation, suggestive of skew deviation, implies central toxicity. This case underscores the potential for diplopia associated with NSAIDs like ibuprofen to be underdiagnosed and offers valuable insights into the central toxicity of ibuprofen. Further research is warranted to elucidate the underlying mechanisms and optimize patient care in similar scenarios.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalDiplopiaIbuprofenAdultBack PainHumansMaleAnti-Inflammatory Agents, Non-SteroidalIbuprofenDiplopiaIbuprofenSkew deviation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.