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ArticleInternational orthopaedics2025

Three dimensional-printed artificial disc replacement for single-level cervical spondylosis: a cohort study.

Xiao-Bo Zhang, Zilin Gao, Xin Yao, Zheng-Wei Xu, Ding-Jun Hao

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Article in International orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Xiao-Bo ZhangDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China.
Zilin GaoDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China.
Xin YaoDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China.
Zheng-Wei XuDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China. irenewayne@126.com.
Ding-Jun HaoDepartment of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, No. 555 Youyi East Road, Nanyoumen, Xi'an, Shaanxi, 710054, China. haodingjun@mail.xjtu.edu.cn.

Funding

Shaanxi Natural Science Basic Research Program. 2021JM-571
6 · The paper itself

Abstract

purposeTo compare the clinical efficacy of 3D-printed artificial discs with that of ACDF for treating cervical spondylosis.

methodsThis was a retrospective analysis of 73 patients with single-level cervical spondylosis who met the inclusion criteria between January 2020 and December 2022 at XX Hospital. The patients were divided: 38 patients in the ACDF group and 35 patients in the CADR group. Patient general information, including operation time and intraoperative blood loss, was collected. The clinical effect of the combination therapy was evaluated by the VAS, JOA, and NDI. The radiological effect was evaluated using the ROM test. Ethics No. 201,606,009.

resultsThe average follow-up times in the ACDF and CADR groups were 28.24 ± 4.65 and 29.11 ± 5.06 months, respectively (P = 0.443). Clinical symptoms (evaluated by VAS, NDI, and JOA) are significantly improved in both the ACDF and CADR groups with similar efficacy. The preoperative ROM of the ACDF group was 40.03 ± 8.79, while that of the CADR group was 42.11 ± 7.98 (P = 0.293). However, the postoperative ROM in the ACDF group was 35.29 ± 7.23, which was lower than that in the CADR group (40.43 ± 6.98) (P = 0.003). Furthermore, only one patient in the ACDF group experienced mild dysphagia after surgery, and the patient recovered within three days. ASD occurred in nine patients in the ACDF group and in two patients in the CADR group (Χ²=4.597, P = 0.032).

conclusionsCompared with ACDF, 3D-printed artificial discs for treating single-level cervical spondylosis have proven to be clinically effective; it associated with less blood loss and a lower incidence of ASD, and maintain a better cervical ROM.

Indexed as

Cervical VertebraePrinting, Three-DimensionalSpondylosisTotal Disc ReplacementAdultCohort StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesSpinal FusionTreatment Outcome3D printedAnterior cervical discectomy and fusionCervical artificial disc replacementCervical spondylosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.