Evidence map›Paper›PMID 39387833›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2024

Correlates and Brain Substrates of Happiness in Community-Dwelling Older Adults in India.

Kelly Cotton, Helena M Blumen, Emmeline Ayers, Dristi Adhikari, Alben Sigamani, Vayyattu G Pradeep Kumar, Joe Verghese

Abstract read
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Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Kelly CottonDepartment of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0001-9014-9762
Helena M BlumenDepartment of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-0275-6616
Emmeline AyersDepartment of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.
Dristi AdhikariDepartment of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.
Alben SigamaniCarmel Research Consultancy Pvt. Ltd, Bengaluru, Karnataka, India.
Vayyattu G Pradeep KumarInstitute of Neurosciences, Baby Memorial Hospital, Kozhikode, Kerala, India.
Joe VergheseDepartment of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0003-4252-2547

Funding

Kerala-Einstein Study: Healthy lifestyle, vascular disease, and cognitive declineR01AG039330 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI MATHURANATH, PAVAGADA S, VERGHESE, JOE · 2011 to 2023
$5.0M
NIA NIH HHS 2R01AG039330-07NIA NIH HHS R01 AG039330
6 · The paper itself

Abstract

objectivesHappiness has been shown to influence many health-related outcomes in older adults. Identifying correlates and brain substrates of happiness across countries and cultures is an important goal, as the global older adult population continues to increase.

methodsWe used univariate and multiple regression to examine associations between happiness and several demographic, health, and lifestyle variables in 665 older adults (39% female) from Kerala, India. We also used Bayesian regression to examine associations between cortical thickness and happiness in a subsample of 188 participants that completed MRI scanning.

resultsHappiness was significantly associated with several variables. In our multiple regression model, which included all significant univariate predictors, self-rated health, depression, anxiety, apathy, social network size, social network diversity, and social support significantly predicted happiness. Demographic indicators (age, sex, education, marital status, residence, and employment status/type), cognitive impairment, comorbidities, and leisure activities were not significantly associated with happiness in the multiple regression model. Cortical thickness in several brain regions was positively associated with happiness scores, including frontal, temporal, parietal, occipital, and cingulate regions. DISCUSSION: Understanding the key correlates is critical for identifying both modifiable factors that can be targeted in well-being interventions and fixed characteristics that identify those at-risk for reduced happiness. The widespread pattern of brain regions associated with happiness is consistent with the multifactorial nature of happiness and, given that the regions identified do not overlap with those vulnerable to cortical thinning, can help explain why subjective well-being, unlike other cognitive functions, is largely resistant to age-related decline.

Indexed as

HappinessIndependent LivingMagnetic Resonance ImagingAgedAged, 80 and overAgingApathyBayes TheoremBrainBrain Cortical ThicknessCerebral CortexDepressionFemaleHealth StatusHumansIndiaCortical thicknessSocial connectionSubjective well-being

Identifiers

PMID39387833
PMCPMC11561394

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.