Evidence map›Paper›PMID 39387550›Full record

ArticleAnnals of medicine2024

Investigation of gut microbiota disorders in norovirus infected children patients based on 16s rRNA sequencing.

Jie Li, Nan Jiang, Hui Zheng, Xiao Zheng, Yi Xu, Yongqing Weng, Feijian Jiang, Chong Wang, Peiliang Chang

Abstract read
In one paragraph

Article in Annals of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jie LiComprehensive Technical Service Center, Taizhou Customs, Taizhou City, Zhejiang, China.
Nan JiangDepartment of Integrated Traditional Chinese and Western Medicine, Taizhou Municipal Hospital, Taizhou City, Zhejiang, China.
Hui ZhengMedical and Chemical Testing Center, Taizhou Institute of Measurement Technology, Taizhou City, Zhejiang, China.
Xiao ZhengSchool Office, Dongshan Central Primary School, Taizhou City, Zhejiang, China.
Yi XuComprehensive Technical Service Center, Taizhou Customs, Taizhou City, Zhejiang, China.
Yongqing WengClinical Laboratory, Taizhou Municipal Hospital, Taizhou City, Zhejiang, China.
Feijian JiangSupervision Section No. 1, Taizhou Customs, Taizhou City, Zhejiang, China.
Chong WangInspection Section, Taizhou Customs, Taizhou City, Zhejiang, China.
Peiliang ChangSupervision Section No. 4, Taizhou Customs, Taizhou City, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNorovirus is the leading cause of sporadic viral gastroenteritis cases and outbreaks. Gut microbiota plays a key role in maintaining immune homeostasis. We aimed to investigate the composition and functional effects of gut microbiota in children infected with norovirus.

methodsStool samples were collected from 31 children infected with norovirus and 25 healthy children. The gut microbiota was analyzed by 16S rRNA gene sequencing, followed by composition, correlation network, functional and phenotype prediction analyses.

resultsGut microbiota in children infected with norovirus was characterized by lower species richness and diversity.

conclusionNorovirus infection may lead to dysregulation of the gut microbiome in children.

Indexed as

Caliciviridae InfectionsFecesGastroenteritisGastrointestinal MicrobiomeNorovirusRNA, Ribosomal, 16SCase-Control StudiesChildChild, PreschoolFemaleHumansInfantMaleRNA, Ribosomal, 16Sfunctional predictiongut microbiotaNorovirus infectionphenotype prediction

Identifiers

PMID39387550
PMCPMC11469441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.