Evidence map›Paper›PMID 39387230›Full record

Observational studyThe British journal of psychiatry : the journal of mental science2024

Investigating inequalities in patient outcomes for first-episode psychosis.

Dasha Nicholls, Jobie Budd, Philippa Nunn, Paul French, Jo Smith, Veenu Gupta, Jonathan Holdship, Alan Quirk

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The British journal of psychiatry : the journal of mental science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dasha NichollsDivision of Psychiatry, Department of Brain Sciences, Imperial College London, London, UK; and Centre for Quality Improvement, Royal College of Psychiatrists, London, UK.ORCID https://orcid.org/0000-0001-7257-6605
Jobie BuddFaculty, London, UK; and Division of Medicine, University College London, London, UK.
Philippa NunnCentre for Quality Improvement, Royal College of Psychiatrists, London, UK.
Paul FrenchCentre for Quality Improvement, Royal College of Psychiatrists, London, UK; Department of Research and Innovation, Pennine Care NHS Foundation Trust, Manchester, UK; and Department of Nursing and Public Health, Manchester Metropolitan University, Manchester, UK.ORCID https://orcid.org/0000-0003-4300-387X
Jo SmithCentre for Quality Improvement, Royal College of Psychiatrists, London, UK; and School of Allied Health and Social Care, University of Worcester, Worcester, UK.
Veenu GuptaCentre for Quality Improvement, Royal College of Psychiatrists, London, UK; and Department of Psychology, Durham University, Durham, UK.
Jonathan HoldshipFaculty, London, UK.
Alan QuirkCentre for Quality Improvement, Royal College of Psychiatrists, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding inequalities in outcomes between demographic groups is a necessary step in addressing them in clinical care. Inequalities in treatment uptake between demographic groups may explain disparities in outcomes in people with first-episode psychosis (FEP).

aimsTo investigate disparities between broad demographic groups in symptomatic improvement in patients with FEP and their relationship to treatment uptake.

methodWe used data from 6813 patients from the 2021-2022 National Clinical Audit of Psychosis data-set. Data were grouped by category type to obtain mean outcomes before adjustment to see whether disparities in outcomes remained after differences in treatment uptake had been accounted for. After matching, the average effect of each demographic variable in terms of outcome change was calculated. Moderator effects on specific treatments were investigated using interaction terms in a regression model.

resultsObservational results showed that patients aged 18-24 years were less likely to improve in outcome, unless adjusted for intervention uptake. Patients classified as Black and Black British were less likely to improve in outcome (moderation effect 0.04, 95% CI 0-0.07) after adjusting for treatment take-up and demographic factors. Regression analysis showed the general positive effect of supported employment interventions in improving outcomes (coefficient -0.13, 95% CI -0.07 to -0.18,

conclusionsInequalities in treatment uptake and psychotic symptom outcome of FEP by social and demographic factors require monitoring over time. Our analysis provides a framework for monitoring health inequalities across national clinical audits in the UK.

Indexed as

Healthcare DisparitiesPsychotic DisordersAdolescentAdultFemaleHumansMaleMiddle AgedOutcome Assessment, Health CareSocioeconomic FactorsUnited KingdomYoung AdultEarly intervention in psychosisethnicityfirst episode psychosisinequalitiesoutcomes.

Identifiers

PMID39387230
PMCPMC11669469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.