Evidence map›Paper›PMID 39387227›Full record

ArticleCancer medicine2024

Network Analyses Applied to the Dimensions of Cancer-Related Fatigue in Women With Breast Cancer.

Louise Baussard, Marie Ernst, Anh Diep, Guy Jerusalem, Audrey Vanhaudenhuyse, Nolwenn Marie, Isabelle Bragard, Marie-Elisabeth Faymonville, Olivia Gosseries, Charlotte Grégoire

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03144154 nacompletednot on this map

Impact of an Intervention Combining Self-care and Hypnosis on the Well-being of Cancer Patients and Their Partners

TypeinterventionalSponsorUniversity of LiegeRan2017 to 2020Enrolled104ConditionsNon-Metastatic NeoplasmArmsSelf-hypnosis + Self-care
NCT04873661 naactive not recruitingnot on this map

Hypnosis, Meditation and Cognitive Trance on Cancer Patients: Impact on Quality of Life and Neurophysiology

TypeinterventionalSponsorUniversity of LiegeRan2021 to 2025Enrolled160ConditionsCancer, Distress, Emotional, Pain, FatigueArmsHypnosis group intervention, Cognitive trance group intervention, Meditation group intervention
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Louise BaussardEpsylon Laboratory, University Paul Valéry Montpellier 3, Nîmes, France.ORCID https://orcid.org/0000-0002-2282-5586
Marie ErnstBiostatistics and Research Methods Centre, University Hospital and University of Liège, Liège, Belgium.
Anh DiepBiostatistics and Research Methods Centre, University Hospital and University of Liège, Liège, Belgium.ORCID https://orcid.org/0000-0001-5134-3220
Guy JerusalemMedical Oncology Department, University Hospital and University of Liège, Liège, Belgium.ORCID https://orcid.org/0000-0002-8845-0043
Audrey VanhaudenhuyseInterdisciplinary Algology Centre, University Hospital of Liège, Liège, Belgium.
Nolwenn MarieSensation and Perception Research Group, GIGA-Consciousness, University of Liège, Liège, Belgium.ORCID https://orcid.org/0000-0003-3159-8423
Isabelle BragardResearch and Continuing Education Department, CRIG Research Center, Haute Ecole Libre Mosane (HELMo), Liège, Belgium.
Marie-Elisabeth FaymonvilleSensation and Perception Research Group, GIGA-Consciousness, University of Liège, Liège, Belgium.
Olivia GosseriesSensation and Perception Research Group, GIGA-Consciousness, University of Liège, Liège, Belgium.
Charlotte GrégoireSensation and Perception Research Group, GIGA-Consciousness, University of Liège, Liège, Belgium.ORCID https://orcid.org/0000-0003-1837-6260

Funding

AstraZeneca FoundationFonds De La Recherche Scientifique - FNRSFonds Léon FredericqKoning Boudewijnstichting 2016-J5120580-205427Plan National Cancer of Belgium 138Stichting Tegen Kanker 2017064Stichting Tegen Kanker C/2020/1357
6 · The paper itself

Abstract

backgroundUnderstanding cancer symptom cluster through network analyses is a new approach in oncology, revealing interconnected and influential relationships among reported symptoms. We aimed to assess these relationships using network analysis in posttreatment breast cancer patients, focusing on the five dimensions of cancer-related fatigue (CRF), and on other common difficulties encountered by oncological patients (i.e., pain, anxiety, depression, sleep difficulties, cognitive impairments, and emotion regulation and mental adaptation difficulties).

methodThis study involved a complementary analysis of data from two interventional studies. Participants completed questionnaires before and after the intervention, with baseline scores being used in this article. Partial correlation network analysis modeled the relationships between symptoms in five distinct networks, each of them including one specific dimension of CRF. The core symptom in each network was identified based on the highest centrality indices.

resultsDepression emerged as the core symptom in all networks, strongly associated with all fatigue dimensions (partial correlations ranging from 0.183 to 0.269) except mental fatigue. These findings indicate robust connections between symptoms, as variations in depression scores directly or indirectly influence fatigue and other symptoms within the cluster.

conclusionOur results support the multidimensional aspect of CRF, and its links with other common symptoms. To effectively reduce patient CRF, interventions should address not only fatigue but also the closely related symptoms from the cluster, such as depression, given its centrality in the cluster.

trial registrationClinicalTrials.gov (NCT03144154 and NCT04873661). Retrospectively registered on May 1, 2017 and April 29, 2021, respectively.

Indexed as

Breast NeoplasmsDepressionFatigueAdultAgedAnxietyFemaleHumansMiddle AgedQuality of LifeRandomized Controlled Trials as TopicSurveys and Questionnairesbreast cancercancer‐related fatiguenetwork analysispsychoneurological symptom cluster

Identifiers

PMID39387227
PMCPMC11465027

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.