Evidence map›Paper›PMID 39387137›Full record

ArticleJournal of feline medicine and surgery2024

Retrospective description of the clinical use of chloramphenicol in client-owned cats: 12 cases (2015-2023).

Vanessa Bruneau, Faye Hartmann, Katrina Viviano

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vanessa BruneauSchool of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Faye HartmannUniversity of Wisconsin Veterinary Care, University of Wisconsin-Madison, Madison WI, USA.
Katrina VivianoSchool of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-1405-1306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aimed to describe the clinical use of chloramphenicol in client-owned cats, examining the patient population, sites of infection, targeted pathogens, prescribed dosing regimen, outcomes and adverse effects.

methodsBetween 2015 and 2023, a retrospective medical record review was undertaken to identify a case series of cats treated with chloramphenicol.

resultsTwelve client-owned cats with complicated infections were treated with chloramphenicol at a median dose of 13.3 mg/kg (range 9.1-34.7) administered orally every 12 h for a median duration of 14.5 days. Within 30 days before starting chloramphenicol, 11/12 cats had received treatment with at least one antibiotic. The sites of infection included skin, urinary tract and multisystemic. Multidrug-resistant pathogens, for which no alternative oral antibiotic therapy was available, were commonly targeted. These included meticillin-resistant CONCLUSIONS AND RELEVANCE: In these cats, the decision to treat with chloramphenicol was made because an alternative oral antibiotic was not available to target the multidrug-resistant pathogens. Infections of the skin or urinary tract were common. Overall, chloramphenicol was well tolerated, and treatment success was possible for most cats.

Indexed as

Anti-Bacterial AgentsCat DiseasesChloramphenicolAnimalsBacterial InfectionsCatsFemaleMaleRetrospective StudiesTreatment OutcomeAnti-Bacterial AgentsChloramphenicolAntibioticsEnterococcus speciesmeticillin-resistant Staphylococcus pseudintermediusmultidrug resistant

Identifiers

PMID39387137
PMCPMC11483659

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.