ReviewFrontiers in endocrinology2024
Neuroprotective effects of magnesium: implications for neuroinflammation and cognitive decline.
Review in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- Magnesium Status in Celiac Disease: Potential Links with Neuroinflammatory Pathways and Gut-Brain Axis Dysfunction.International journal of molecular sciences · 2026Review
- Protective effect of magnesium on indomethacin-induced gastric ulcer in mice.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Magnesium Supplementation Improves Cortical Stratification and Neuronal Differentiation in Blood-Brain Barrier-Integrated Human Brain Organoids.Biomedicines · 2026Article
- Magnesium at the Neurovascular Interface: A Narrative Review of Atherosclerosis, Peripheral Arterial Disease, and Neuropathic Pain.Nutrients · 2026Review
- Magnesium in Neurocritical Care: Clinical Relevance, Status Assessment, and Practical Implications for Outcomes-A Narrative Review.Nutrients · 2026Review
- The Therapeutic Home Environment for Chronic Diseases: A Transdisciplinary Ecosystem for Achieving Migraine Freedom and Managing Comorbid Anxiety, Insomnia, and Chronic Pain.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Adjunctive Intravenous Magnesium Sulfate for Postoperative Pain and Opioid Reduction in Lower Extremity Orthopedic Surgery: A Double-Blind Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Magnesium - The Silent Partner or the Next Vitamin D? Shifting Paradigm in Mineral Metabolism in Health and Disease.EJIFCC · 2026Article
- Diabetes-induced Multiorgan Damage: Can Magnesium Delay the process?Current nutrition reports · 2026Review
- Mapping the future of medicine through digital twins.Frontiers in molecular medicine · 2026Review
- U-shaped pattern in the association between serum magnesium levels and long-term dementia risk after traumatic brain injury: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Association Between Domestic Water Hardness and MRI-Based Measures of Brain Volume: Evidence from the UK Biobank.Health data science · 2026Article
- Maternal and Fetal Magnesium Balance: Impacts and Implications.Advances in experimental medicine and biology · 2026Review
- Review
- Unraveling the Effects ofInternational journal of molecular sciences · 2025Review
- Article
- Depression and Hypomagnesemia as Independent and Synergistic Predictors of Cognitive Impairment in Older Adults Post-COVID-19: A Prospective Cohort Study.Medical sciences (Basel, Switzerland) · 2025Article
- Is dolichol pathway dysfunction a significant factor in Alzheimer's disease?Inflammopharmacology · 2025Review
- The Role of Magnesium in Depression, Migraine, Alzheimer's Disease, and Cognitive Health: A Comprehensive Review.Nutrients · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurodegenerative diseases, which are characterized by progressive neuronal loss and cognitive decline, are a significant concern for the aging population. Neuroinflammation, a shared characteristic of these diseases, is implicated in their pathogenesis. This article briefly summarizes the role of magnesium, an essential mineral involved in numerous enzymatic reactions and critical for neuronal bioactivity, in the context of neuroinflammation and cognitive decline. The potential neuroprotective effects of magnesium, including the mechanisms of neuroprotection by magnesium through maintaining neuronal ion homeostasis, reducing inflammation, and preventing excitotoxicity, are also described. Additionally, we discuss the impact of inadequate magnesium on neuroinflammation and its potential as a therapeutic agent for attenuating cognitive decline to improve neurodegenerative conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.