Evidence map›Paper›PMID 39386982›Full record

ArticleRoyal Society open science2024

An experimental and computational investigation of the cyclopentene-containing peptide-derived compounds: focus on pseudo-cyclic motifs via intramolecular interactions.

Joanna Bojarska, Martin Breza, Paweł Borowiecki, Izabela D Madura, Krzysztof Kaczmarek, Zyta M Ziora, Wojciech M Wolf

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joanna BojarskaChemistry Department, Institute of Ecological and Inorganic Chemistry, Technical University of Lodz, 116 Zeromskiego St., Lodz 90-924, Poland.ORCID https://orcid.org/0000-0001-9190-6913
Martin BrezaDepartment of Physical Chemistry, Slovak Technical University, Radlinskeho 9, Bratislava SK-81237, Slovakia.
Paweł BorowieckiLaboratory of Biocatalysis and Biotransformation, Department of Drugs Technology and Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 75 Koszykowa St., Warsaw 00-662, Poland.
Izabela D MaduraFaculty of Chemistry, Warsaw University of Technology, 3 Noakowskiego St., Warsaw 00-664, Poland.
Krzysztof KaczmarekInstitute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, 116 Zeromskiego St., Lodz 90-924, Poland.
Zyta M ZioraInstitute for Molecular Bioscience, The University of Queensland, St Lucia QLD 4072, Australia.
Wojciech M WolfChemistry Department, Institute of Ecological and Inorganic Chemistry, Technical University of Lodz, 116 Zeromskiego St., Lodz 90-924, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conformational flexibility is one of the main disadvantages of peptide-based compounds. We focus on their molecular 'chameleonicity' related to forming pseudo-cyclic motifs via modulation of weak intramolecular interactions. It is an appealing strategy for controlling equilibrium between the polar open and the nonpolar closed conformations. Within this context, we report here the crystal structure of the (

Indexed as

cyclopenteneDFTenergy frameworksHirshfeld surfacemodified amino acidssingle crystal

Identifiers

PMID39386982
PMCPMC11462612

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.