Evidence map›Paper›PMID 39386855›Full record

ArticleHeliyon2024

Transcriptome and RNA sequencing analysis of H9C2 cells exposed to diesel particulate matter.

Kyoung Jin Nho, Jae Hoon Shin, Jin Ee Baek, Sung Won Choi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kyoung Jin NhoDepartment of Pathogenic Laboratory Research, Institute of Occupation and Environment, Korea Workers' Compensation & Welfare Service, 478, Munemi-ro, Bupyeong-gu, Incheon, 21417, Republic of Korea.
Jae Hoon ShinDepartment of Pathogenic Laboratory Research, Institute of Occupation and Environment, Korea Workers' Compensation & Welfare Service, 478, Munemi-ro, Bupyeong-gu, Incheon, 21417, Republic of Korea.
Jin Ee BaekDepartment of Pathogenic Laboratory Research, Institute of Occupation and Environment, Korea Workers' Compensation & Welfare Service, 478, Munemi-ro, Bupyeong-gu, Incheon, 21417, Republic of Korea.
Sung Won ChoiDepartment of Pathogenic Laboratory Research, Institute of Occupation and Environment, Korea Workers' Compensation & Welfare Service, 478, Munemi-ro, Bupyeong-gu, Incheon, 21417, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although air pollution has been classified as a risk factor for heart disease, the underlying mechanisms remain nebulous. Therefore, this study investigated the effect of diesel particulate matter (DPM) exposure on cardiomyocytes and identified differentially expressed genes (DEGs) induced by DPM. DPM treatment decreased H9C2 cell viability and increased cytotoxicity. Ten genes showed statistically significant differential expression following treatment with DPM at 25 and 100 μg/ml for 3 h. A total of 273 genes showed statistically significant differential expression following treatment with DPM at 25 and 100 μg/ml for 24 h. Signaling pathway analysis revealed that the DEGs were related to the 'reactive oxygens species,' 'IL-17,' and 'fluid shear stress and atherosclerosis' signaling pathways.

Indexed as

Gene expression profilingGene ontologyMyocardiumParticulate matterSequence analysis

Identifiers

PMID39386855
PMCPMC11462235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.