An open-source combined atomic force microscope and optical microscope for mechanobiology studies.

Daniel Delgado, Sarah Desroches, Gia Kang, Yousef Aldabii, Andrew R Harris

Abstract read

In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Cellular mechanisms of traumatic brain injury.npj biological physics and mechanics · 2025
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel DelgadoDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, Ontario, Canada, K1S 5B6.

Sarah DesrochesDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, Ontario, Canada, K1S 5B6.

Gia KangDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, Ontario, Canada, K1S 5B6.

Yousef AldabiiDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, Ontario, Canada, K1S 5B6.

Andrew R HarrisDepartment of Mechanical and Aerospace Engineering, Carleton University, 1125 Colonel by Drive, Ottawa, Ontario, Canada, K1S 5B6.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atomic Force Microscopy (AFM) has become the gold standard tool for measuring mechanical properties of biological samples including proteins, single cells and tissues. However, investment in this specialized equipment and gaining expertise in its operation are significant obstacles for non-experts looking to adopt this technique. To address this, we have designed an AFM based mechanical measurement system for measuring cell mechanical properties which is combined with a custom inverted fluorescence microscope which can be used for characterizing mechanosensitive responses. This system, through its ease of use and low setup cost, will promote interdisciplinary research leading to new insights into the role of cell mechanics and mechanosensitive responses in physiology and disease.

Identifiers

PMID39386786

DOI10.1016/j.heliyon.2024.e38214

PMCPMC11462344

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.