Evidence map›Paper›PMID 39386775›Full record

ArticleHeliyon2024

Pilot scale manufacturing of black seed oil-loaded alginate beads; process development, and stability of thymoquinone.

Hamzeh Alkhatib, Farahidah Mohamed, Mulham Alfatama, Elham Assadpour, Mohammad Saeed Kharazmi, Seid Mahdi Jafari, Md Zaidul Islam Sarker, Kishor Kumar Sadasivuni, Awis Sukarni Mohmad Sabere, Abd Almonem Doolaanea

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hamzeh AlkhatibDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University College of MAIWP International (UCMI), 68100, Kuala Lumpur, Malaysia.
Farahidah MohamedDepartment of Pharmaceutical Technology, Kulliyyah of Pharmacy, International Islamic University Malaysia, 25200, Kuantan, Pahang, Malaysia.
Mulham AlfatamaFaculty of Pharmacy, Universiti Sultan Zainal Abidin, Besut Campus, Kuala Terengganu, 22200, Malaysia.
Elham AssadpourFood Industry Research Co., Gorgan, Iran.
Mohammad Saeed KharazmiFaculty of Medicine, University of California, Riverside, USA.
Seid Mahdi JafariDepartment of Food Materials and Process Design Engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran.
Md Zaidul Islam SarkerCooperative Research, Extension & Education Services (CEES), Northern Marianas College, P.O. Box 501250, Saipan, MP, 96950, USA.
Kishor Kumar SadasivuniCenter for Advanced Materials, Qatar University, P. O. Box 2713, Doha, Qatar.
Awis Sukarni Mohmad SabereDepartment of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, 25200, Kuantan, Pahang, Malaysia.
Abd Almonem DoolaaneaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University College of MAIWP International (UCMI), 68100, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The approach of ionic gelation was employed at the pilot scale of the 50 kg batch size to manufacture black seed oil (BSO)-loaded alginate (ALG) beads as a natural source supplementing the main bioactive compound of BSO, i.e., thymoquinone (TQ). The BSO-ALG emulsion was prepared by initially emulsifying BSO with alginate solution at the pilot scale in two stages. The final emulsion was then dripped through 12 units of 3D-printed multi-nozzles into a curing bath containing Ca

Indexed as

Alginate beadsBlack seed oilIonic gelationScale-upStabilityThymoquinone

Identifiers

PMID39386775
PMCPMC11462023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.