Evidence map›Paper›PMID 39386636›Full record

ArticlebioRxiv : the preprint server for biology2025

Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids.

Andrea I Boyd, Leah A Kafer, Isabel F Escapa, Amal Kambal, Hira Tariq, Susan G Hilsenbeck, Hoa Nguyen-Phuc, Anubama Rajan, Joshua M Lensmire, Kathryn A Patras and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Andrea I BoydDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-4079-4813
Leah A KaferDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-7355-9636
Isabel F EscapaDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-1454-7205
Amal KambalDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Hira TariqDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Susan G HilsenbeckDuncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-7962-673X
Hoa Nguyen-PhucDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Anubama RajanDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-4773-4362
Joshua M LensmireDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Kathryn A PatrasDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-2631-8810
Pedro A PiedraDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-5839-0879
Sarah E BluttDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Katherine P LemonDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-1542-1679

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Viral Diversity and Pathogenicity in Mucosal Respiratory and Gastrointestinal DiseaseU19AI144297 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ESTES, MARY KOLB, GIBBS, RICHARD A · 2019 to 2024
$30.1M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
Novel Platforms for Human Intestinal Enteroids: Matrix, Mechanics, and TopographyU19AI116497 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GRANDE-ALLEN, KATHRYN JANE · 2015 to 2025
$13.2M
Organoid Cultivation CoreU19AI157981 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A, LEMON, KATHERINE PAIGE · 2021 to 2025
$12.4M
Effect of Mucins and Dolosigranlulum pigrum on Staphylococcus aureus nasal colonizationF31AI172324 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BOYD, ANDREA IVEY · 2023 to 2025
$146k
NCI NIH HHS P30 CA125123NIAID NIH HHS F31 AI172324NIAID NIH HHS U19 AI116497NIAID NIH HHS U19 AI144297NIAID NIH HHS U19 AI157981NIDDK NIH HHS P30 DK056338NIEHS NIH HHS P30 ES030285
6 · The paper itself

Abstract

Nasal colonization by

Indexed as

bacterial colonizationDolosigranulum pigrumepithelial innate immune responseHNOhuman nasal organoidsMRSAnasal colonizationStaphylococcus aureusStreptococcus pneumoniae

Identifiers

PMID39386636
PMCPMC11463382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.