Evidence map›Paper›PMID 39386608›Full record

ArticlebioRxiv : the preprint server for biology2024

Interactions among Merlin, Arkadia, and SKOR2 mediate NF2-associated Schwann cell proliferation in human.

Pei-Ciao Tang, Seyoung Um, Anderson B Mayfield, Olena R Bracho, Christian Del Castillo, Christine T Dinh, Derek M Dykxhoorn, Xue Zhong Liu

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Pei-Ciao TangEqual contribution: Pei-Ciao Tang and Seyoung Um.
Seyoung UmEqual contribution: Pei-Ciao Tang and Seyoung Um.
Anderson B MayfieldCoral Reef Diagnostics.
Olena R BrachoDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.
Christian Del CastilloDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.
Christine T DinhDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.
Derek M DykxhoornDr. John T Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.
Xue Zhong LiuDepartment of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, 33136, United States.

Funding

Molecular Genetics on Non Syndromic Hearing Loss (NSHL)R01DC005575 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIU, XUE Z · 2001 to 2024
$10.6M
Sensory disorders in COVID -19 as an early identifier and healthcare worker protectionR01DC012115 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LIU, XUE Z · 2013 to 2022
$7.2M
Preclinical Testing of PI3K Inhibitors for Vestibular SchwannomasR01DC017264 · NIDCD · UNIVERSITY OF CENTRAL FLORIDA · PI FERNANDEZ-VALLE, CRISTINA MARIA, LIU, XUE Z · 2018 to 2022
$3.1M
Miami Otolaryngology Surgeon-Scientist Training Program (MOSSTP)R25DC020726 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Christine Thuyvan Dinh · 2023 to 2026
$988k
Tumor-Mediated Hearing Loss in Neurofibromatosis Type IIK08DC017508 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DINH, CHRISTINE THUYVAN · 2019 to 2023
$840k
Cell fate determination in the early development of the otic lineage in human inner ear organoidsR21DC019450 · NIDCD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI TANG, PEI-CIAO · 2021 to 2023
$447k
NIDCD NIH HHS K08 DC017508NIDCD NIH HHS R01 DC005575NIDCD NIH HHS R01 DC012115NIDCD NIH HHS R01 DC017264NIDCD NIH HHS R21 DC019450NIDCD NIH HHS R25 DC020726
6 · The paper itself

Abstract

NF2-Related Schwannomatosis (previously referred to as Neurofibromatosis Type 2, or NF2) is a genetic-associated disease resulting from mutations in the gene,

Indexed as

Arkadiahuman pluripotent stem cellmerlinNF2NF2-Related SchwannomatosisproteomicsSchwann cellSKOR2TGFβ

Identifiers

PMID39386608
PMCPMC11463491

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.