Evidence map›Paper›PMID 39386574›Full record

ArticlebioRxiv : the preprint server for biology2024

In Situ UNIversal Orthogonal Network (UNION) Bioink Deposition for Direct Delivery of Corneal Stromal Stem Cells to Corneal Wounds.

Lucia G Brunel, Betty Cai, Sarah M Hull, Uiyoung Han, Thitima Wungcharoen, Gabriella Maria Fernandes-Cunha, Youngyoon Amy Seo, Patrik K Johansson, Sarah C Heilshorn, David Myung

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Thitima WungcharoenORCID 0000-0002-3461-8015
Gabriella Maria Fernandes-CunhaORCID 0000-0002-9934-5310
Youngyoon Amy Seo
Patrik K JohanssonORCID 0000-0003-1652-3781
Sarah C HeilshornORCID 0000-0002-9801-6304

Funding

3D bioprinting of regenerative, corneal cell-laden inks to treat corneal blindnessF31EY034785 · NEI · STANFORD UNIVERSITY · PI BRUNEL, LUCIA · 2023 to 2024
$82k
NEI NIH HHS F31 EY034785
6 · The paper itself

Abstract

The scarcity of human donor corneal graft tissue worldwide available for corneal transplantation necessitates the development of alternative therapeutic strategies for treating patients with corneal blindness. Corneal stromal stem cells (CSSCs) have the potential to address this global shortage by allowing a single donor cornea to treat multiple patients. To directly deliver CSSCs to corneal defects within an engineered biomatrix, we developed a UNIversal Orthogonal Network (UNION) collagen bioink that crosslinks

Identifiers

PMID39386574
PMCPMC11463654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.