Evidence map›Paper›PMID 39386458›Full record

ArticlebioRxiv : the preprint server for biology2025

Simulation-based survey of TMEM16 family reveals that robust lipid scrambling requires an open groove.

Christina A Stephens, Niek van Hilten, Lisa Zheng, Michael Grabe

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Christina A StephensCardiovascular Research Institute, University of California, San Francisco, CA 94158.ORCID 0000-0001-9382-003X
Niek van HiltenCardiovascular Research Institute, University of California, San Francisco, CA 94158.ORCID 0000-0003-1204-2489
Lisa ZhengCardiovascular Research Institute, University of California, San Francisco, CA 94158.ORCID 0000-0002-8640-2443
Michael GrabeCardiovascular Research Institute, University of California, San Francisco, CA 94158.ORCID 0000-0003-3509-5997

Funding

Ion permeation, lipid flipping, and membrane remodeling by TMEM16 proteinsR01GM137109 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRABE, MICHAEL · 2021 to 2024
$1.4M
NIGMS NIH HHS R01 GM137109
6 · The paper itself

Abstract

Biological membranes are complex and dynamic structures with different populations of lipids in their inner and outer leaflets. The Ca

Indexed as

MD simulationmembrane deformationscramblasesTMEM16s

Identifiers

PMID39386458
PMCPMC11463437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.