Evidence map›Paper›PMID 39386220›Full record

ArticleBioactive materials2025

Decellularized liver scaffolds for constructing drug-metabolically functional

Juan Liu, Ariel Hanson, Wenzhen Yin, Qiao Wu, Eliane Wauthier, Jinmei Diao, Timothy Dinh, Jeff Macdonald, Ruihong Li, Masahiko Terajima and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. A Systematic Review on Artificial Liver for Implantation.Journal of functional biomaterials · 2026
    Review
  5. Review
  6. Organoid scaffold materials: research and application.Frontiers in bioengineering and biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Juan LiuHepato-pancreato-biliary Center, Clinical Translational Science Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Ariel HansonDepartments of Biomedical Engineering, UNC School of Medicine, Chapel Hill, NC, 27599, USA.
Wenzhen YinHepato-pancreato-biliary Center, Clinical Translational Science Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Qiao WuInfection Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, China.
Eliane WauthierDepartments of Cell Biology and Physiology, UNC School of Medicine, Chapel Hill, NC, 27599, USA.
Jinmei DiaoHepato-pancreato-biliary Center, Clinical Translational Science Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Timothy DinhDepartments of Genetics, UNC School of Medicine, Chapel Hill, NC, 27599, USA.
Jeff MacdonaldDepartments of Biomedical Engineering, UNC School of Medicine, Chapel Hill, NC, 27599, USA.
Ruihong LiHepato-pancreato-biliary Center, Clinical Translational Science Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Masahiko TerajimaOral and Craniofacial Health Sciences, UNC School of Dentistry, Chapel Hill, NC, 27599, USA.
Mitsuo YamauchiOral and Craniofacial Health Sciences, UNC School of Dentistry, Chapel Hill, NC, 27599, USA.
Ziye ChenHepato-pancreato-biliary Center, Clinical Translational Science Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Praveen SethupathyDepartments of Genetics, UNC School of Medicine, Chapel Hill, NC, 27599, USA.
Jiahong DongHepato-pancreato-biliary Center, Clinical Translational Science Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.
Lola M ReidDepartments of Biomedical Engineering, UNC School of Medicine, Chapel Hill, NC, 27599, USA.
Yunfang WangHepato-pancreato-biliary Center, Clinical Translational Science Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China.

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROBERT S. SANDLER · 1985 to 2026
$30.5M
Discovery of microRNA regulatory modules controlling human pancreatic islet functR00DK091318 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SETHUPATHY, PRAVEEN · 2012 to 2014
$737k
Validation of penta-omic assays in brain tissue and identification of markers of tissue and -omic data qualityR21AG088936 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MACDONALD, JEFFREY M., MIECZKOWSKI, PIOTR ANDRZEJ · 2024 to 2024
$440k
NCI NIH HHS P30 CA016086NIA NIH HHS R21 AG088936NIDDK NIH HHS P30 DK034987NIDDK NIH HHS R00 DK091318
6 · The paper itself

Abstract

The creation of

Indexed as

Drug-induced liver injuryHuman tissue engineered liverLiver biomatrix scaffoldsMetabolism

Identifiers

PMID39386220
PMCPMC11462156

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.