Evidence map›Paper›PMID 39386092›Full record

ArticleFrontiers in allergy2024

Gut microbiome features in pediatric food allergy: a scoping review.

Margherita Farnetano, Laura Carucci, Serena Coppola, Franca Oglio, Antonio Masino, Marica Cozzolino, Rita Nocerino, Roberto Berni Canani

Erratum issuedAbstract readScoping Review
In one paragraph

Article in Frontiers in allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Margherita Farnetano *Department of Translational Medical Science, University of Naples Federico II, Naples, Italy.
Laura Carucci *Department of Translational Medical Science, University of Naples Federico II, Naples, Italy.
Serena CoppolaDepartment of Translational Medical Science, University of Naples Federico II, Naples, Italy.
Franca OglioDepartment of Translational Medical Science, University of Naples Federico II, Naples, Italy.
Antonio MasinoDepartment of Translational Medical Science, University of Naples Federico II, Naples, Italy.
Marica CozzolinoDepartment of Translational Medical Science, University of Naples Federico II, Naples, Italy.
Rita NocerinoDepartment of Translational Medical Science, University of Naples Federico II, Naples, Italy.
Roberto Berni CananiDepartment of Translational Medical Science, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence suggests that alterations in the gut microbiome (GM) play a pivotal role in the pathogenesis of pediatric food allergy (FA). This scoping review analyzes the current evidence on GM features associated with pediatric FAs and highlights the importance of the GM as a potential target of intervention for preventing and treating this common condition in the pediatric age. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, we searched PubMed and Embase using the keywords (gut microbiome OR dysbiosis OR gut microbiota OR microbiome signatures) AND (food allergy OR IgE-mediated food allergy OR food protein-induced allergic proctocolitis OR food protein-induced enterocolitis OR non-IgE food allergy OR cow milk allergy OR hen egg allergy OR peanut allergy OR fish allergy OR shellfish allergy OR tree nut allergy OR soy allergy OR wheat allergy OR rice allergy OR food sensitization). We included 34 studies reporting alterations in the GM in children affected by FA compared with healthy controls. The GM in pediatric FAs is characterized by a higher abundance of harmful microorganisms (e.g., Enterobacteriaceae,

Indexed as

allergychildrencow milk protein allergydysbiosisimmune tolerancemicrobiotaprobioticsshort-chain fatty acids

Identifiers

PMID39386092
PMCPMC11461474

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.