Evidence map›Paper›PMID 39386078›Full record

ArticleBiochemistry and biophysics reports2024

"Protective effects of artichoke extract and Bifidobacterium longum on male infertility in diabetic rats".

Zahra Ansari, Mohammad Hasan Maleki, Fatemeh Roohy, Zahra Ebrahimi, Mesbah Shams, Pooneh Mokaram, Zahra Zamanzadeh, Zahra Hosseinzadeh, Farhad Koohpeyma, Sanaz Dastghaib

Abstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Therapeutic Potential ofInternational journal of endocrinology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zahra AnsariDepartment of Genetics, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University, Esfahan, Iran.
Mohammad Hasan MalekiDepartment of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Fatemeh RoohyDepartment of Genetics, Islamic Azad University, Kazerun, Iran.
Zahra EbrahimiDepartment of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Mesbah ShamsEndocrinology and Metabolism Research Center, Shiraz University of Medical Science, P.O. Box, 71345-1744, Shiraz, Iran.
Pooneh MokaramAutophagy Research Center, Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra ZamanzadehDepartment of Genetics, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University, Esfahan, Iran.
Zahra HosseinzadehEndocrinology and Metabolism Research Center, Shiraz University of Medical Science, P.O. Box, 71345-1744, Shiraz, Iran.
Farhad KoohpeymaEndocrinology and Metabolism Research Center, Shiraz University of Medical Science, P.O. Box, 71345-1744, Shiraz, Iran.
Sanaz DastghaibEndocrinology and Metabolism Research Center, Shiraz University of Medical Science, P.O. Box, 71345-1744, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes is a major global health concern and plays a significant role in male infertility and hormonal abnormalities by altering the tissue structure of spermatogenic tubes and decreasing the number of spermatogonia. This study investigated the effect of artichoke ( Methods: In this experiment, 96 male-rats were randomly selected from eight groups. Control, Sham (normal saline), DM group (IP injected with 60 mg/kg STZ), Cynara (400 mg/kg hydroalcoholic extract of Cynara scolymus L), BBL (received 1 × 10 Results: In comparison to the diabetic group, the hydroalcoholic extract of Conclusion: The findings demonstrated that Cynara scolymus L extract and Bifidobacterium longum supplement had great therapeutic potential, including antioxidant, anti-apoptotic, anti-diabetic, fertility index improvement, and sex hormone modulators.

Indexed as

Anti-oxidantApoptosisdiabetesMale infertilitySpermatogenesis

Identifiers

PMID39386078
PMCPMC11462217

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.