Evidence map›Paper›PMID 39385673›Full record

ArticlePediatrics2024

Increase in Cases of Perinatal HIV Transmission in Maryland in 2022.

David C Griffith, Matthew Grant, Wei Li Adeline Koay, Natella Rakhmanina, Anna Maya Powell, Allison Agwu

Abstract read
In one paragraph

Article in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David C GriffithDepartments of Pediatrics.
Matthew GrantDivision of Community Pediatrics and Adolescent Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Wei Li Adeline KoayDivision of Infectious Diseases, Children's National Hospital, Washington, District of Columbia.
Natella RakhmaninaDivision of Infectious Diseases, Children's National Hospital, Washington, District of Columbia.
Anna Maya PowellObstetrics and Gynecology, Johns Hopkins School of Medicine, Baltimore, Maryland.
Allison AgwuDepartments of Pediatrics.

Funding

Vaginal Microbiome and Metabolites in Preterm BirthK23AI155296 · NIAID · JOHNS HOPKINS UNIVERSITY · PI POWELL, ANNA MAYA · 2021 to 2025
$991k
NIAID NIH HHS K23 AI155296
6 · The paper itself

Abstract

The perinatal transmission of HIV is preventable through a regimen that includes testing of all pregnant individuals, antiretroviral treatment (ART) for the pregnant individual, prophylactic or preventative ART for the infant, and cesarean section delivery for mothers with HIV viremia at the time of delivery. Under this protocol, the United States has seen a significant decline in the perinatal transmission of HIV and achieved a perinatal HIV transmission rate of 0.9% in 2019. However, despite this progress nationally and after zero transmissions in 2021, Maryland recorded 6 cases of perinatal HIV diagnoses in 2022. Each of the 3 major referral centers for pediatric HIV patients in Maryland reported 2 new cases in 2022. A root cause analysis of the cases identified risk factors including delayed entry into perinatal and HIV care, premature birth, maternal adherence challenges in the setting of substance use and other adverse social determinants of health, and failure to diagnose maternal HIV infection in a timely way. All patients were successfully linked to care and initiated on ART. Multiple factors contributed to the 2022 increase in cases of perinatal HIV in Maryland. To achieve and then sustain the elimination of perinatal HIV transmission, the constancy of systems that eliminate barriers for all pregnant people to access testing, prevention, and treatment is critical.

Indexed as

HIV InfectionsInfectious Disease Transmission, VerticalPregnancy Complications, InfectiousFemaleHumansInfant, NewbornMarylandPregnancyRisk Factors

Identifiers

PMID39385673
PMCPMC12272831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.