Evidence map›Paper›PMID 39385504›Full record

ReviewPhytotherapy research : PTR2024

Exploring Bioactive Phytomedicines for Advancing Pulmonary Infection Management: Insights and Future Prospects.

Joyce Siaw Syuen Ho, Teh Li Ping, Keshav Raj Paudel, Tammam El Sherkawi, Gabriele De Rubis, Stewart Yeung, Philip M Hansbro, Brian Gregory George Oliver, Dinesh Kumar Chellappan, Keng Pei Sin and 1 more

Abstract readReview
In one paragraph

Review in Phytotherapy research : PTR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joyce Siaw Syuen HoDepartment of Pharmaceutical Chemistry, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.
Teh Li PingDepartment of Pharmaceutical Chemistry, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.
Keshav Raj PaudelCentre for Inflammation, School of Life Sciences, Faculty of Science, Centenary Institute and the University of Technology Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0002-3591-2080
Tammam El SherkawiDiscipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.
Gabriele De RubisDiscipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0001-7088-396X
Stewart YeungDiscipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.
Philip M HansbroCentre for Inflammation, School of Life Sciences, Faculty of Science, Centenary Institute and the University of Technology Sydney, Sydney, Australia.
Brian Gregory George OliverSchool of Life Science, University of Technology Sydney, Ultimo, Australia.
Dinesh Kumar ChellappanDepartment of Life Sciences, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.
Keng Pei SinDepartment of Pharmaceutical Chemistry, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.
Kamal DuaDiscipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0002-7507-1159

Funding

Maridulu Budyari Gumal-The Sydney Partnership for Health, Education, Research and Enterprise (SPHERE)Triple I Skills Advancement Grant 2023UMCG Research FundsUniversity of Technology Sydney Key Technology Partner (UTS-KTP)
6 · The paper itself

Abstract

Pulmonary infections have a profound influence on global mortality rates. Medicinal plants offer a promising approach to address this challenge, providing nontoxic alternatives with higher levels of public acceptance and compliance, particularly in regions where access to conventional medications or diagnostic resources may be limited. Understanding the pathophysiology of viruses and bacteria enables researchers to identify biomarkers essential for triggering diseases. This knowledge allows the discovery of biological molecules capable of either preventing or alleviating symptoms associated with these infections. In this review, medicinal plants that have an effect on COVID-19, influenza A, bacterial and viral pneumonia, and tuberculosis are discussed. Drug delivery has been briefly discussed as well. It examines the effect of bioactive constituents of these plants and synthesizes findings from in vitro, in vivo, and clinical studies conducted over the past decade. In conclusion, many medicinal plants can be used to treat pulmonary infections, but further in-depth studies are needed as most of the current studies are only at preliminary stages. Extensive investigation and clinical studies are warranted to fully elucidate their mechanisms of action and optimize their use in clinical practice.

Indexed as

Plants, MedicinalAnimalsCOVID-19COVID-19 Drug TreatmentHumansInfluenza, HumanPhytochemicalsPhytotherapyPlant ExtractsSARS-CoV-2PhytochemicalsPlant ExtractsCOVID‐19influenzamedicinal plantspneumoniapulmonary infectiontuberculosis

Identifiers

PMID39385504
PMCPMC11634825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.