Evidence map›Paper›PMID 39385328›Full record

ArticleAutophagy2025

Autophagy controls neuronal differentiation by regulating the WNT-DVL signaling pathway.

Vincencius Vidyawan, Lesly Puspita, Virginia Blessy Juwono, Magdalena Deline, Kelvin Pieknell, Mi-Yoon Chang, Sang-Hun Lee, Jae-Won Shim

Abstract read
In one paragraph

Article in Autophagy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vincencius VidyawanSoonchunhyang Institute of Medi-Bio Science (SIMS), Soonchunhyang University, Cheonan-Si, Korea.
Lesly PuspitaSoonchunhyang Institute of Medi-Bio Science (SIMS), Soonchunhyang University, Cheonan-Si, Korea.
Virginia Blessy JuwonoSoonchunhyang Institute of Medi-Bio Science (SIMS), Soonchunhyang University, Cheonan-Si, Korea.
Magdalena DelineSoonchunhyang Institute of Medi-Bio Science (SIMS), Soonchunhyang University, Cheonan-Si, Korea.
Kelvin PieknellGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Korea.
Mi-Yoon ChangGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Korea.
Sang-Hun LeeGraduate School of Biomedical Science and Engineering, Hanyang University, Seoul, Korea.ORCID 0000-0001-7553-8188
Jae-Won ShimSoonchunhyang Institute of Medi-Bio Science (SIMS), Soonchunhyang University, Cheonan-Si, Korea.ORCID 0000-0003-4071-3710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macroautophagy/autophagy dysregulation is associated with various neurological diseases, including Vici syndrome. We aimed to determine the role of autophagy in early brain development. We generated neurons from human embryonic stem cells and developed a Vici syndrome model by introducing a loss-of-function mutation in the

Indexed as

AutophagyDishevelled ProteinsHuman Embryonic Stem CellsWnt ProteinsAgenesis of Corpus CallosumCataractCell DifferentiationHumansLysosomesMicrocephalyNeural Stem CellsNeuronsPhenotypeSignal TransductionWnt Signaling PathwayDishevelled ProteinsWnt ProteinsEPG5human embryonic stem cellsmacroautophagyneuronal differentiationVici syndromeWNT signal pathway

Identifiers

PMID39385328
PMCPMC12506719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.