Evidence map›Paper›PMID 39385244›Full record

ReviewInfectious agents and cancer2024

The role of helminths and their antigens in cancer therapy: insights from cell line models.

Gita Alizadeh, Ali Kheirandish, Maryam Alipour, Mahnaz Jafari, Mahdis Radfar, Tina Bybordi, Raheleh Rafiei-Sefiddashti

Abstract readReview
In one paragraph

Review in Infectious agents and cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gita AlizadehDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Ali KheirandishDepartment of Pharmacology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Maryam AlipourDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mahnaz JafariDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mahdis RadfarDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Tina BybordiDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Raheleh Rafiei-SefiddashtiDepartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. r.rafiei.sd@gmail.com.ORCID http://orcid.org/0000-0001-5489-823X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent articles have explored the effect of worms on cancer cells. This review focused on various cell cultures employed to understand which cells are more commonly and less utilized.

methodsThe present review analyzed studies published between 2013 and 2023 to obtain information about different cell cultures used in cancer studies involving helminths. Databases such as PubMed, Google Scholar, HINARI, and the Cochrane Library were searched.

resultsThis search yielded 130 records, but 97 papers were excluded because they were either irrelevant to the research topic (n = 72) or contradicted the research idea (n = 25).The remaining twenty-one articles focused on different types of worms, such as Echinococcus granulosus, Clonorchis sinensis, Opisthorchis felineus, Opisthorchis viverrini, Trichinella spiralis, Toxocara canis, and Heligmosomoides polygyrus.

conclusionDue to the presence of numerous antigens, parasites at different growth stages can impact various cells through unknown mechanisms. Given the high diversity of antigens and their effects, artificial intelligence can assist in predicting initial outcomes for future studies.

Indexed as

AntigenCancerHelminthsTreatment

Identifiers

PMID39385244
PMCPMC11465614

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.