Observational studyBMC women's health2024
The suture fixation of the levonorgestrel-releasing intrauterine device with hysteroscope for the treatment of adenomyosis in patients at high risk of device expulsion-a prospective observational study.
Observational study in BMC women's health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- GyneFix levonorgestrel-releasing intrauterine system for Chinese patients: a preliminary retrospective self-controlled observational study.BMC women's health · 2026Observational
- A case report of removal and uterine suturing of an incarcerated intrauterine sterilization ring.The Journal of international medical research · 2026Article
- Anchoring levonorgestrel-releasing intrauterine system versus suture fixation of the levonorgestrel-releasing intrauterine system in the treatment of adenomyosis.BMC surgery · 2026Article
- Comparative effectiveness of two hysteroscopic fixation techniques (suture vs. GyneFix anchor) for levonorgestrel-releasing intrauterine system: a retrospective study.BMC women's health · 2026Article
- A Narrative Review and Risk-Stratification Framework for Preventing LNG-IUS Expulsion in Adenomyosis.Therapeutics and clinical risk management · 2026Review
- Clinical value of hysteroscopic levonorgestrel intrauterine system suture fixation in treating adenomyosis.BMC women's health · 2025Article
- Uterine transverse diameter and risk of LNG-IUS malposition in adenomyosis patients: a threshold effect analysis from a retrospective cohort study.BMC women's health · 2025Article
- Hysteroscopic sutureless fixation of the levonorgestrel-releasing intrauterine system in the treatment of heavy menstrual bleeding.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to investigate the safety and efficacy of suture fixation of the levonorgestrel-releasing intrauterine device (LNG-IUD) by hysteroscope for the treatment of adenomyosis in patients at high risk of device expulsion, to provide a viable treatment option for these patients.
methodsTwenty-one patients with large symptomatic adenomyosis were sewed and fixed with the LNG-IUD in the uterus by hysteroscopy to prevent the device expulsion.
resultsIn this prospective case series, all 21 patients were successfully sewed and fixed with the LNG-IUD in the uterus by hysteroscopy. The amount of menstruation was significantly decreased and dysmenorrhea was significantly relieved in 3, 6, and 12 months after surgery compared with before surgery. Only one patient underwent a laparoscopic hysterectomy due to dysmenorrhea which was not alleviated one month later. Serious IUD complications including expulsion and perforation were not observed. There was no development of new side effects than LNG-IUD insertion.
conclusionOur findings indicate that suture fixation of the LNG-IUD by hysteroscope is a safe, effective, and minimally invasive surgical procedure to prevent the device expulsion. It is a good solution for the treatment of large symptomatic adenomyosis and has shown to be effective in managing symptoms related to adenomyosis.
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