Evidence map›Paper›PMID 39385155›Full record

SynthesisBMC oral health2024

The impact of electronic cigarette use on periodontitis and periodontal outcomes: a systematic review and meta-analysis.

Muhammed Shabil, Mahalaqua Nazli Khatib, Suhas Ballal, Pooja Bansal, Balvir S Tomar, Ayash Ashraf, M Ravi Kumar, Aashna Sinha, Pramod Rawat, Abhay M Gaidhane and 6 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Muhammed Shabil *University Center for Research and Development, Chandigarh University, Mohali, Punjab, India.
Mahalaqua Nazli Khatib *Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, India.
Suhas BallalDepartment of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
Pooja BansalDepartment of Allied Healthcare and Sciences, Vivekananda Global University, Jaipur, Rajasthan, 303012, India.
Balvir S TomarInstitute of Pediatric Gastroenterology and Hepatology, NIMS University, Jaipur, India.
Ayash AshrafChandigarh Pharmacy College, Chandigarh Group of College, Jhanjeri, Mohali, Chandigarh, Punjab, 140307, India.
M Ravi KumarDepartment of Chemistry, Raghu Engineering College, Visakhapatnam, Andhra Pradesh, 531162, India.
Aashna SinhaSchool of Applied and Life Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, India.
Pramod RawatDepartment of Biotechnology, Graphic Era (Deemed to be University), Clement Town Dehradun, Dehradun, 248002, India.
Abhay M GaidhaneGlobal Health Academy, School of Epidemiology and Public Health, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education, Wardha, India. abhay.psm@dmiher.edu.in.
Sanjit SahSR Sanjeevani Hospital, Kalyanpur, Siraha, 56517, Nepal. sanjitsahnepal561@gmail.com.
Ganesh BushiSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India.
Mahendra Pratap SinghCenter for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Saveetha Medical College and Hospital, Saveetha University, Chennai, India.
Kiran BhopteIES Institute of Pharmacy, IES University, Bhopal, Madhya Pradesh, 462044, India.
Arkadiusz DziedzicDepartment of Conservative Dentistry with Endodontics, Medical University of Silesia, Katowice, Poland. adziedzic@sum.edu.pl.
Manvi PantNew Delhi Institute of Management, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeriodontitis, a prevalent inflammatory disease affecting tooth-supporting structures, leads to significant oral health and systemic complications if untreated. While traditional smoking is a well-known risk factor for periodontitis, the impact of electronic cigarettes (e-cigarettes) on periodontal health remains unclear. This systematic review and meta-analysis aim to synthesize existing evidence on the effects of e-cigarette use on periodontitis and other periodontal outcomes.

methodsA literature search was conducted across PubMed, EMBASE, and Web of Science from their inception up to June 15 2024. Eligible studies included those assessing the impact of e-cigarette use on periodontal outcomes such as bleeding on probing (BOP), plaque index, probing depth, clinical attachment loss, and marginal bone loss. Data were extracted and analyzed using random-effect models to calculate pooled mean differences. R statistical software was used to perform meta-analyses.

resultsTwelve studies were included in the meta-analysis. E-cigarette users showed a significantly lower mean BOP score compared to non-users (pooled mean difference: -14.233; 95% CI: -20.424 to -8.043; I² = 99%). For other periodontal outcomes, the findings were as follows: Plaque Index (MD: -0.160; 95% CI: -0.680 to 0.360; I² = 95%), Clinical Attachment Loss (MD: 0.120; 95% CI: -0.045 to 0.285; I² = 90%), Probing Depth (MD: 0.056; 95% CI: -0.070 to 0.182; I² = 85%), and Marginal Bone Loss (MD: -0.052; 95% CI: -0.168 to 0.064; I² = 88%).

conclusionPresent studies have not identified a significant link between e-cigarette use and adverse effects on periodontal health, but the available research is limited. Further longitudinal research is necessary to evaluate the long-term effects of e-cigarette use on periodontal health and to clarify any associated risks.

Indexed as

Electronic Nicotine Delivery SystemsPeriodontitisVapingAlveolar Bone LossDental Plaque IndexHumansPeriodontal Attachment LossPeriodontal IndexDental healthE-cigaretteMeta-analysisOral healthPeriodontitis

Identifiers

PMID39385155
PMCPMC11463078

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.