Evidence map›Paper›PMID 39385065›Full record

SynthesisBMC cardiovascular disorders2024

The effect of glucomannan supplementation on lipid profile in adults: a GRADE-assessed systematic review and meta-analysis.

Vali Musazadeh, Rogheye Yaraee Rostami, Amir Hossein Moridpour, Zahra Bokaii Hosseini, Omid Nikpayam, Maryam Falahatzadeh, Amir Hossein Faghfouri

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vali Musazadeh *Student research committee, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Rogheye Yaraee Rostami *School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Amir Hossein MoridpourStudent Research Committee, Department of Nutritional Sciences, School of Nutrition Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Zahra Bokaii HosseiniFaculty of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Omid NikpayamDepartment of Nutritional Sciences, School of Health, Golestan University of Medical Sciences, Gorgan, Iran.
Maryam FalahatzadehDepartment of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran. maryamfalahatzade.mf@gmail.com.
Amir Hossein FaghfouriMaternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran. Amir.nut89@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlucomannan has been studied for various health benefits, but its effects on lipid profile in adults are not well understood. This meta-analysis aims to evaluate the impact of glucomannan supplementation on serum/plasma levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), Apo B1, Apo A1, APO-B/ A1 ratio, and LDL-C/ HDL-C in adults.

methodsA comprehensive search was conducted across Scopus, PubMed, Embase, and Web of Science from inception to June 2024 to identify randomized controlled trials (RCTs) assessing glucomannan supplementation on lipid profile in adults. Data were extracted and analyzed using random effects model to determine the standardized mean differences (SMDs) and 95% confidence intervals (CIs) for each biomarker.

resultsGlucomannan supplementation significantly decreased TC (SMD: -3.299; 95% CI: -4.955, -1.664, P < 0.001; I

conclusionsGlucomannan supplementation has a beneficial effect on the level of TC and LDL-C.

Indexed as

BiomarkersDietary SupplementsLipidsMannansAdultDyslipidemiasHumansRandomized Controlled Trials as TopicTreatment Outcome(1-6)-alpha-glucomannanBiomarkersLipidsMannansDyslipidemiaGlucomannanLipid profileLipoproteinMeta-analysisSystematic review

Identifiers

PMID39385065
PMCPMC11465682

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.