Evidence map›Paper›PMID 39384972›Full record

ArticleSpinal cord2025

Does the presence or absence of preoperative lower extremity neurologic symptoms influence postoperative clinical outcome in patients with cervical intradural extramedullary tumors?: a single-center retrospective comparative study.

Toshiki Okubo, Narihito Nagoshi, Takahito Iga, Kazuki Takeda, Masahiro Ozaki, Satoshi Suzuki, Morio Matsumoto, Masaya Nakamura, Kota Watanabe

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Spinal cord, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Toshiki OkuboDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-0912-7422
Narihito NagoshiDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan. nagoshi@keio.jp.ORCID 0000-0001-8267-5789
Takahito IgaDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Kazuki TakedaDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Masahiro OzakiDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Satoshi SuzukiDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Morio MatsumotoDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Masaya NakamuraDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Kota WatanabeDepartment of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-4830-4690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective comparative study

objectivesTo investigate whether the presence or absence of preoperative lower extremities neurological symptoms (LENS) influences clinical outcomes following tumor resection in patients with cervical intradural extramedullary (IDEM) tumors.

settingThe single institution in Japan.

methodsNinety-two patients with cervical IDEM tumors requiring surgical resection were included. Based on the degree of preoperative LENS assessed using the modified McCormick scale (MMCS), patients were categorized into LENS (-) and (+) groups. Demographic and surgical characteristics were compared between both groups.

resultsThere were no significant differences observed in sex, tumor location, tumor size, surgical time, estimated blood loss, approach for tumorectomy, or tumor histopathology between the two groups. Additionally, the overall surgical outcomes were favorable for both groups. At the final follow-up, 91.1% of the patients in the LENS (+) group were able to walk without support. Improvement in LENS was observed after surgery in most patients with preoperative MMCS II-IV, but it persisted in approximately 40% of patients with preoperative MMCS V. In the LENS (+) group, there were no significant differences in demographic or surgical data between the patients with MMCS I and II-III at the final follow-up.

conclusionsRegardless of the presence or absence of preoperative LENS, clinical improvement was observed after tumor resection in most patients with cervical IDEM tumors. These findings suggest that neurological status is likely to improve sufficiently if tumor resection is performed before preoperative LENS deteriorates to an extremely severe stage as MMCS V.

Indexed as

Lower ExtremitySpinal Cord NeoplasmsAdultAgedCervical VertebraeFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.