Evidence map›Paper›PMID 39384897›Full record

ArticleNPJ digital medicine2024

Individualized decision making in on-scene resuscitation time for out-of-hospital cardiac arrest using reinforcement learning.

Dong Hyun Choi, Min Hyuk Lim, Ki Jeong Hong, Young Gyun Kim, Jeong Ho Park, Kyoung Jun Song, Sang Do Shin, Sungwan Kim

Abstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dong Hyun Choi *Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, South Korea.ORCID http://orcid.org/0000-0001-6036-1404
Min Hyuk Lim *Graduate School of Health Science and Technology, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.ORCID http://orcid.org/0000-0003-1547-2804
Ki Jeong HongDepartment of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, South Korea. emkjhong@gmail.com.ORCID http://orcid.org/0000-0003-3334-817X
Young Gyun KimInterdisciplinary Program in Bioengineering, Graduate School, Seoul National University, Seoul, South Korea.ORCID http://orcid.org/0000-0003-1231-9097
Jeong Ho ParkDepartment of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, South Korea.
Kyoung Jun SongLaboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, South Korea.
Sang Do ShinDepartment of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, South Korea.
Sungwan KimDepartment of Biomedical Engineering, Seoul National University College of Medicine, Seoul, South Korea. sungwan@snu.ac.kr.ORCID http://orcid.org/0000-0002-9318-849X

Funding

Korea Health Industry Development Institute (KHIDI) MD-PhD/Medical Scientist Training grantNational Research Foundation of Korea (NRF) RS-2023-00251482
6 · The paper itself

Abstract

On-scene resuscitation time is associated with out-of-hospital cardiac arrest (OHCA) outcomes. We developed and validated reinforcement learning models for individualized on-scene resuscitation times, leveraging nationwide Korean data. Adult OHCA patients with a medical cause of arrest were included (N = 73,905). The optimal policy was derived from conservative Q-learning to maximize survival. The on-scene return of spontaneous circulation hazard rates estimated from the Random Survival Forest were used as intermediate rewards to handle sparse rewards, while patients' historical survival was reflected in the terminal rewards. The optimal policy increased the survival to hospital discharge rate from 9.6% to 12.5% (95% CI: 12.2-12.8) and the good neurological recovery rate from 5.4% to 7.5% (95% CI: 7.3-7.7). The recommended maximum on-scene resuscitation times for patients demonstrated a bimodal distribution, varying with patient, emergency medical services, and OHCA characteristics. Our survival analysis-based approach generates explainable rewards, reducing subjectivity in reinforcement learning.

Identifiers

PMID39384897
PMCPMC11464506

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.