Evidence map›Paper›PMID 39384883›Full record

ArticleScientific reports2024

Genome-wide association study of subfoveal choroidal thickness in a longitudinal cohort of older adults.

Hyeong Min Kim, Kwangsic Joo, Minji Kim, Young Joo Park, Ji Won Han, Ki Woong Kim, Sejoon Lee, Se Joon Woo

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyeong Min KimDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 173-82 Gumi-ro, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Kwangsic JooDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 173-82 Gumi-ro, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Minji KimDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 173-82 Gumi-ro, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Young Joo ParkDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 173-82 Gumi-ro, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea.
Ji Won HanDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Ki Woong KimDepartment of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Sejoon LeePrecision Medicine Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Se Joon WooDepartment of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 173-82 Gumi-ro, Bundang-gu, Seongnam-si, 13620, Gyeonggi-do, Republic of Korea. sejoon1@snu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To identify genetic influences on subfoveal choroidal thickness of older adults using a genome-wide association study (GWAS). We recruited 300 participants from the population-based Korean Longitudinal Study on Health and Aging (KLoSHA) and Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) cohort studies and 500 participants from the Bundang age-related macular degeneration (AMD) cohort study dataset. We conducted a GWAS on older adult populations in the KLoSHA and KLOSCAD cohorts. Single nucleotide polymorphisms (SNPs) associated with choroidal thickness were identified with P values < 1.0 × 10

Indexed as

ChoroidGenome-Wide Association StudyPolymorphism, Single NucleotideAgedAged, 80 and overCohort StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansHuman Umbilical Vein Endothelial CellsLongitudinal StudiesMacular DegenerationMaleAge-related macular degeneration (AMD)Choroidal thicknessCUL3FAM124BGWASHUVECSingle nucleotide polymorphism (SNP)

Identifiers

PMID39384883
PMCPMC11464807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.